Investigation of consortia formation by periodontopathic bacteria

点击翻译按钮获取中文摘要

In this project, our goal was to investigate bacterial interaction in the process of biofilm formation to clarify the virulence of periodontopathic bacteria in dental plaque. In the process of colonization, P. gingivalis adhered to T. denticola by means of Hgp44, which is located on its surface. A synergistic effect was observed in co-culture of F. nucleatum and P. intermedia, C. ochracea, or P. gingivalis. In addition, invasion of epithelial cells by P. gingivalis was enhanced by co-infection with F. nucleatum or P. gingivalis. These results suggest that organization as consortia confers an advantage on periodontopathic bacteria in the formation of dental plaque.