Roles of phospholipase C deltal in hair shaft formation
Roles of phospholipase C deltal in hair shaft formation
批准号:
21790292
负责人:
NAKAMURA Yoshikazu
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
FOXN1是一种转录因子,对头发的形成至关重要。磷脂酶C(PLC)δ1是磷脂酰肌醇信号通路中的一个关键分子,对正常毛发的形成是必不可少的。在这项研究中,我们发现Foxn1介导的PLCδ1的表达在正常毛发形成和Notch1的表达中是重要的。
英文摘要
A transcription factor, FOXN1 is essential for hair formation. Phospholipase C (PLC)δ1, a key molecule in the phosphoinositide signaling pathway, is essential for normal hair formation. In this study, we found that Foxn1-mediated expression of PLCδ1 is important in normal hair formation and Notchl expression.
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Phospholipase C-deltal Regulates Hair Keratin Expression And Hair Shaft Formation Downstream of Foxnl.
磷脂酶 C-deltal 调节 Foxnl 下游的毛发角蛋白表达和毛干形成。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[鈴木睦実, 平田真之, 石井里佳, 中村由和, 深見希代子, Y.Nakamura ; M.Ichinohe ; S.Takahashi ; S.Inanobe ; K.Kanemaru ; K.Fukami]
通讯作者:
Y.Nakamura ; M.Ichinohe ; S.Takahashi ; S.Inanobe ; K.Kanemaru ; K.Fukami
PHYSIOLOGICAL FUNCTIONS OF BIO ACTIVE LIPID PRODUCER, PHOSPHOLIPASE C-DELTA1 IN SKIN
皮肤中生物活性脂质生产者磷脂酶 C-Delta1 的生理功能
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Nakamura Y., Fukami K.]
通讯作者:
Fukami K.
Phosphatidylinositol 4,5-bisphosphate and PIP5-kinase Iα are required for invadopodia formation in human breast cancer cells
人乳腺癌细胞侵袭伪足的形成需要磷脂酰肌醇 4,5-二磷酸和 PIP5 激酶 Iα
DOI:
--
发表时间:
2010
期刊:
Cancer Sci. (In press)
影响因子:
--
作者:
[芝崎 太, 内野博之, Tanaka M, Yamaguchi H]
通讯作者:
Yamaguchi H
ホスホリパーゼC-delta1による毛形成制御機構
磷脂酶 C-delta1 控制毛发形成的机制
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[高橋佐織, 中村由和, 一戸学, 深見希代子]
通讯作者:
深見希代子
Physiological functions of phospholipase C δ1 in adipose tissue development and obesity (part1)
磷脂酶Cδ1在脂肪组织发育和肥胖中的生理功能(第一部分)
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Ishii, R., Hirata, M., Suzuki, M., Matsuoka, S., Nakamura, Y., Kouchi, Z., Yamaguchi, H., Sasaki, T., Kitamurea, T., Fukami, K.]
通讯作者:
K.
共 33 条
The role of phosphoinositide metabolism in the interaction of different cell types in skin and tumor
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批准号:24790295
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.83万
-
财政年份:2012
-
负责人:NAKAMURA Yoshikazu
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依托单位:
Sequence Complementarity -Independence Functional RNAs
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批准号:18107005
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$72.38万
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财政年份:2006
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负责人:NAKAMURA Yoshikazu
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依托单位:
Structural and functional study of translation apparatus from the viewpoint of molecular mimicry and prion transmission
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批准号:14035207
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$83.78万
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财政年份:2002
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负责人:NAKAMURA Yoshikazu
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依托单位:
Structural and functional study of translational release factor from the viewpoint of molecular mimicry and prion transmission
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批准号:13308040
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$29.45万
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财政年份:2001
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负责人:NAKAMURA Yoshikazu
-
依托单位:
Spatiotemporal Network of RNA Information Flow
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批准号:13051101
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$208.19万
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财政年份:2001
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负责人:NAKAMURA Yoshikazu
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依托单位:
Drug discovery and design based on molecular mimicry
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批准号:11557190
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.58万
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财政年份:1999
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负责人:NAKAMURA Yoshikazu
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依托单位:
Molecular Mimicry in Translation
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批准号:11694195
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项目类别:Grant-in-Aid for Scientific Research (A).
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资助金额:$14.27万
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财政年份:1999
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负责人:NAKAMURA Yoshikazu
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依托单位:
Molecular basis of RNA function
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批准号:09278102
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas (A)
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资助金额:$132.1万
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财政年份:1997
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负责人:NAKAMURA Yoshikazu
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依托单位:
Regulation of Translation Termination
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批准号:08044196
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$22.85万
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财政年份:1996
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负责人:NAKAMURA Yoshikazu
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依托单位:
Study of Pneumocystis carinii : from Molecular Microbiology to Drug Discovery
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批准号:07557027
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$13.44万
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财政年份:1995
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负责人:NAKAMURA Yoshikazu
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依托单位:
PHILOLOGICAL STUDY ON RELIGIOUS MOMENTS IN OLD RUSSIAN AND EARLY MODERN RUSSIAN LITERATURE
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批准号:06301053
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$4.35万
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财政年份:1994
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负责人:NAKAMURA Yoshikazu
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依托单位:
Post-Transcriptional Control of Gene Expression : mRNA Degradation and Translational Regulation
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批准号:04044052
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$19.2万
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财政年份:1992
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负责人:NAKAMURA Yoshikazu
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依托单位:
Role of Russian-Slavic Culture in Japanese Modernization
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批准号:02301067
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项目类别:Grant-in-Aid for Co-operative Research (A)
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资助金额:$4.93万
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财政年份:1990
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负责人:NAKAMURA Yoshikazu
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依托单位:
Molecular Biology of Pneumocystis Carinii and its Clinical Application
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批准号:02454175
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.97万
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财政年份:1990
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负责人:NAKAMURA Yoshikazu
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依托单位:
Synthetic Studies on Russian and East European View on Japan and its Chages
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批准号:63301064
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项目类别:Grant-in-Aid for Co-operative Research (A)
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资助金额:$4.1万
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财政年份:1988
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负责人:NAKAMURA Yoshikazu
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依托单位:
海外基金