A new strategy to conquer obesity by use of a newly discovered neuropeptide GALP

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GALP is known as a neuropeptide whish regulates feeding and energy metabolism but there is no reports to use of GALP for obese animals efficiently. In this study, we have established the intranasal infusion method of GALP for animals. We have studied obese animals such as ob/ob, db/db and DIO mice and we got the data that intranasal infusion of GALP was very effective on these animals to loose body weight and food intake. It is suggested that intranasal infusion of GALP is useful for obese people to conquer obesity and life-style related diseases in future.