Structure analysis of Nectin and Nectin like protein family
Structure analysis of Nectin and Nectin like protein family
批准号:
22570115
负责人:
SUZUKI Mamoru
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
We determined the crystal structures of the entire extracellular region of nectin-1,2,3. In the crystal, nectin formed a V-shaped homophilic dimer through the first Ig-like domain. Structure-based site-directed mutagenesis experimental results indicate that, in contrast with the previous notion, our structure represents a cis-dimer. Thus, our findings clearly reveal the structural basis for the cis-dimerization of nectins through the first Ig-like domains.
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Crystal Structure Analysis of Nectin and Nectin-Like-Molecule Family(II)
Nectin及Nectin类分子家族的晶体结构分析(II)
DOI:
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发表时间:
2012
期刊:
影响因子:
--
作者:
[中倉 由香子, 秋吉 由佳里, 合田 名都子, 成田 宏隆, 鈴木 守, 天野 剛志, 浜田大三, 藤原 芳江, 中川 敦史, 古瀬 幹夫, 廣明 秀一, 成田宏隆・藤原芳江・中川敦史・鈴木 守, Mamoru Suzuki]
通讯作者:
Mamoru Suzuki
A little more until sunrise
还有一点点,直到日出
DOI:
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发表时间:
2012
期刊:
影响因子:
--
作者:
[Chavas LM, Matsugaki N, Yamada Y, Hiraki M, Igarashi N, Suzuki M, Wakatsuki S, L. M. G. Chavas, 鈴木守, Mamoru Suzuki]
通讯作者:
Mamoru Suzuki
細胞接着装置の制御に関わるLNX1PDZ2の構造・機能解析
LNX1PDZ2参与调节细胞粘附机制的结构和功能分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[中倉 由香子, 秋吉 由佳里, 合田 名都子, 成田 宏隆, 鈴木 守, 天野 剛志, 浜田大三, 藤原 芳江, 中川 敦史, 古瀬 幹夫, 廣明 秀一]
通讯作者:
廣明 秀一
Suzuki' s Home Page
铃木的主页
DOI:
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发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
細胞接着分子ネクチンおよびネクチン様分子のX線結晶構造
细胞粘附分子Nectin和Nectin类分子的X射线晶体结构
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[中倉 由香子, 秋吉 由佳里, 合田 名都子, 成田 宏隆, 鈴木 守, 天野 剛志, 浜田大三, 藤原 芳江, 中川 敦史, 古瀬 幹夫, 廣明 秀一, 成田宏隆・藤原芳江・中川敦史・鈴木 守]
通讯作者:
成田宏隆・藤原芳江・中川敦史・鈴木 守
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