Regulation of cell division by tyrosine phosphorylation signaling and its role in cancer development
Regulation of cell division by tyrosine phosphorylation signaling and its role in cancer development
批准号:
22590056
负责人:
NAKAYAMA Yuji
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Cell division is tightly regulated in order to prevent cancers, cancer progression and cell death. In this study, we showed that tyrosine phosphorylation signaling by Src-family tyrosine kinases is important for regulation of mitotic spindle formation. In addition, cytokinesis fails upon an increase in Src activity, resulting in generation of binucleated cells.
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分裂期スピンドル形成におけるSrcシグナリング
有丝分裂纺锤体形成中的 Src 信号传导
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[橋本裕輝, 内藤展江, 森俊訓, 轟木堅一郎, 糸山美紀, 巴山忠, 吉田秀幸, 能田均, 山口政俊, Ishikawa T, 武田祐美]
通讯作者:
武田祐美
Degradation of filamin induces contraction of vascular smooth muscle cells in Type-I collagen matrix honeycombs.
细丝蛋白的降解诱导 I 型胶原基质蜂窝中血管平滑肌细胞的收缩。
DOI:
10.1159/000330076
发表时间:
2011
期刊:
Cellular Physiology and Biochemistry
影响因子:
--
作者:
[Tomizawa, A., Hadjidekov, G., Ishii, I.. Bakalova, R., Zhelev, Z., Aoki, I., Saga, T., Kitada, M., Uchida M Ishii I Hirata K Yamamoto F Tashiro K Suzuki T Nakayama Y Ariyoshi N and Kitada M.]
通讯作者:
Uchida M Ishii I Hirata K Yamamoto F Tashiro K Suzuki T Nakayama Y Ariyoshi N and Kitada M.
Src型チロシンキナーゼによる分裂期スピンドルの安定化.
Src 型酪氨酸激酶稳定有丝分裂纺锤体。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Izumikawa T., et al., 岡本麻依]
通讯作者:
岡本麻依
Src型チロシンキナーゼFynの中心体局在と紡錘体形成における機能
Src型酪氨酸激酶Fyn在纺锤体形成中的中心体定位和功能
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Jun Maeda, Masaki Tokunaga, Ming-Rong Zhang, Takeharu Minamihisamatsu, Toshimitsu Fukumura, Tsuyoshi Miyakawa, Tetsuya Suhara, Makoto Higuchi, 岡本麻依,長谷川智津,中山祐治,武田祐美,盛永敬郎,福本泰典,山口直人]
通讯作者:
岡本麻依,長谷川智津,中山祐治,武田祐美,盛永敬郎,福本泰典,山口直人
DOI:
10.1016/j.ejcb.2011.12.008
发表时间:
2012-05-01
期刊:
EUROPEAN JOURNAL OF CELL BIOLOGY
影响因子:
6.6
作者:
[Matsui, Yuki, Nakayama, Yuji, Yamaguchi, Naoto]
通讯作者:
Yamaguchi, Naoto
共 13 条
Chromosomal cloning of FXS-related chromosomal fragile site including pathongenic CGG triplet repeat
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批准号:18K06183
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2018
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负责人:NAKAYAMA Yuji
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依托单位:
Construction of cell-culture based assay system to understand CGG repeat instability in Fragile X syndrome
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批准号:24770005
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
-
财政年份:2012
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负责人:NAKAYAMA Yuji
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依托单位:
In vitro production of the Camel heavy chain antibody toward development of alternative antibody medicine
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批准号:22780304
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.0万
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财政年份:2010
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负责人:NAKAYAMA Yuji
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依托单位:
Regulation of cell division by tyrosine phosphorylation-mediated control of organelle dynamics
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批准号:19590058
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:NAKAYAMA Yuji
-
依托单位:
A Research on Marketing Channel: its development, management, and restructuring
-
批准号:19730285
-
项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.48万
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财政年份:2007
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负责人:NAKAYAMA Yuji
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依托单位:
海外基金