The mechanism and overcome of resistance to anti-VEGF antibody, bevacizumab in colon cancer
The mechanism and overcome of resistance to anti-VEGF antibody, bevacizumab in colon cancer
批准号:
22591478
负责人:
TAKAHASHI Yutaka
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
We studied the mechanism and overcome of resistance to anti-VEGF antibody , bevacizumab. We could not find any upregulated genes in transplanted tumors and clinical tumors which were resistant to bevacizumab while bevacizumab therapies by several microarray studies. These results suggest that the resistance to anti-VEGF would be rare rather than conventional cancer drugs and other molecular targeting drugs.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI:
--
发表时间:
2011
期刊:
Front Biosci
影响因子:
--
作者:
[Takahashi Y, et al]
通讯作者:
et al
DOI:
--
发表时间:
2011
期刊:
Front Biosci
影响因子:
--
作者:
[小川仁, ほか, 伊藤 誠二, Takahashi Y and Nishioka K]
通讯作者:
Takahashi Y and Nishioka K
DOI:
10.1097/cad.0b013e328345b509
发表时间:
2011-07-01
期刊:
ANTI-CANCER DRUGS
影响因子:
2.3
作者:
[Komatsu, Yoshito, Takahashi, Yutaka, Saji, Shigetoyo]
通讯作者:
Saji, Shigetoyo
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