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The role for Rap1 signaling in the trafficking of germinal centerB cells

The role for Rap1 signaling in the trafficking of germinal centerB cells
Rap1 信号在生发中心 B 细胞运输中的作用
批准号:
23790547
负责人:
UEDA Yoshihiro
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
翻译
我们发现,在Rap1效应RAPL和Mst1-/-小鼠中,二次抗体反应增强。LFA-1-/-B细胞显示正常生发中心和记忆B细胞生成的事实表明,在RAPL和Mst1-/-小鼠增强抗体产生的过程中,对B细胞反应的调节不依赖于LFA。
英文摘要
We found that secondary antibody responses were enhanced in Rap1-effector RAPL and Mst1-/- mice. The fact that LFA-1-/- B cells showed normal germinal center and memory B cell generation suggests LFA-independent regulation of B cell response in enhanced antibody production of RAPL and Mst1-/- mice.
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会议论文
Crucial roles of LFA-1 regulation in thymocyte trafficking and antigen recognition by Mst1.
LFA-1 调节在胸腺细胞运输和 Mst1 抗原识别中的关键作用。
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [木村彰宏, Ueda Yoshihiro, UEDA Yoshihiro]
通讯作者: UEDA Yoshihiro
Mst1 regulates thymocyte trafficking and antigen recognition within thymic tissues
Mst1 调节胸腺组织内的胸腺细胞运输和抗原识别
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Ueda Yoshihiro1, Katagiri Koko2, Tomiyama Takashi1, Yasuda Kaneki1, Habiro Katsuyoshi1, Katakai Tomoya1, Ikehara Susumu3, Kinashi Tatsuo1, (1Department of Molecular Genetics, Institute of Biomedical Science, Kansai Medical University. 2Department of Biosc]
通讯作者: Kansai Medical University. 2Department of Biosc
Crucial roles of LFA-1 regulation in thymocyte trafficking and antigen recognitionby Mst1
LFA-1 调节在胸腺细胞运输和 Mst1 抗原识别中的关键作用
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [木村彰宏, Ueda Yoshihiro]
通讯作者: Ueda Yoshihiro
Spatiotemporal regulation of NKT cell production by Rap1 GTPase
  • 批准号:
    20K07554
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.75万
  • 财政年份:
    2020
  • 负责人:
    UEDA Yoshihiro
  • 依托单位:
Spatiotemporal regulation of thymic Treg production by Rap1GTPase
  • 批准号:
    16K08849
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.08万
  • 财政年份:
    2016
  • 负责人:
    UEDA Yoshihiro
  • 依托单位:
Complete Search for Buried, Rapidly Growing Supermassive Black holes with Multiwavelength Observations
  • 批准号:
    23540265
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.24万
  • 财政年份:
    2011
  • 负责人:
    UEDA Yoshihiro
  • 依托单位:
Stability and nonlinear structure for the nonlinear partial differential equations of gas dynamics.
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