Analysis of anti-fibrotic effects of lipid-responsible transcription factors and a search for new therapeutic agents -with special attention to hypoxic insults-
Analysis of anti-fibrotic effects of lipid-responsible transcription factors and a search for new therapeutic agents -with special attention to hypoxic insults-
批准号:
24591193
负责人:
KIMURA Hideki
金额:
$3.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2015-03-31
中文摘要
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英文摘要
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ヒト培養メサンギウム細胞において,テルミサルタンはTGF-β誘導性PAI-1産生をPPAR-δ経路を介して抑制する.
在培养的人系膜细胞中,替米沙坦通过 PPAR-δ 途径抑制 TGF-β 诱导的 PAI-1 产生。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[岩田恭宜1,2, 橋本真一1, 横田恭宣1, 古市賢吾2, 和田隆志, 三上大輔]
通讯作者:
三上大輔
A heterozygous female with Fabry disease due to a novel alpha-galactosidase A mutation exhibits a unique synaptopodin distribution in vacuolated podocytes
由于新型 α-半乳糖苷酶 A 突变而患有法布里病的杂合女性在空泡足细胞中表现出独特的突触蛋白分布
DOI:
--
发表时间:
2015
期刊:
Clin Nephrol
影响因子:
1.1
作者:
[N.Takahashi, S.Yokoi, K.Kasuno, A.Kogami, T.Tsukimura, T.Togawa, S.Saito, K.Ohno, M.Hara, H.Kurosawa, Y.Hirayama, T.Kurose, Y.Yokoyama, D.Mikami, H.Kimura, H.Naiki, H.Sakuraba, M.Iwano]
通讯作者:
M.Iwano
蛋白尿の種類と検査法ー新規バイオマーカーを含めてー
蛋白尿的类型和测试方法 - 包括新的生物标志物 -
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Iwata Y, Furuichi K, Wada T, Nagamori S., 赤松弘朗, 木村 秀樹]
通讯作者:
木村 秀樹
Urinary Podocalyxin Refl ects Podocyte Injury in Hypoxia-Exacerbated Diabetic Glomerulosclerosis
尿足萼蛋白反映缺氧加剧的糖尿病肾小球硬化症的足细胞损伤
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Lei B, Nakano D, Fujisawa Y, Liu Y, Hitomi H, Kobori H, Mori H, Masaki T, Asanuma K, Tomino Y, Nishiyama A., Tkahashi Naoki]
通讯作者:
Tkahashi Naoki
新規TLR4阻害因子・分泌型FSP1を介したポドサイトーメサンギウム細胞連関
由新型 TLR4 抑制剂和分泌型 FSP1 介导的足细胞-系膜细胞关联
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[横井靖二、岩野正之, 他]
通讯作者:
他
共 18 条
Investigation for anti-renal fibrotic effects of lipid-binding proteins and lipid-activated nuclear receptors and search for new therapeutic reagents
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批准号:21591024
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2009
-
负责人:KIMURA Hideki
-
依托单位:
Diachronic Changes and Panchronic Universal Properties of Constructions and Grammatical Categories in Chinese-a Reconstruction of Historical Chinese Grammar
-
批准号:19320057
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.9万
-
财政年份:2007
-
负责人:KIMURA Hideki
-
依托单位:
Analysis for anti-inflammatory and anti-fibrotic actions of lipid transfer proteins and lipid-activated transcription factors in the progressive renal injury
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批准号:19590944
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2007
-
负责人:KIMURA Hideki
-
依托单位:
Investigation on anti-inflammatory effects of lipid-binding proteins and lipophilic transcriptional factors in progression of renal injury.
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批准号:17590823
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2005
-
负责人:KIMURA Hideki
-
依托单位:
Diachronic Changes and Panchronic Universal Properties of Constructions and Grammatical Categories in Chinese-a Reconstruction of Historical Chinese Grammar
-
批准号:16320049
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.98万
-
财政年份:2004
-
负责人:KIMURA Hideki
-
依托单位:
Investigation on anti-inflammatory effects of lipid-binding proteins in progression of renal injury.
-
批准号:14571021
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2002
-
负责人:KIMURA Hideki
-
依托单位:
Research onChinese Construction Categories and Event Perception
-
批准号:13610533
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2001
-
负责人:KIMURA Hideki
-
依托单位:
BIOCHEMICAL AND HISTOCHEMICAL EXAMINATIONS ON LIPJD-BINDING PROTEINS (LBP), PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) AND RETINOL RECEPTORS (RXR) IN KIDNEY.
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批准号:12671034
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2000
-
负责人:KIMURA Hideki
-
依托单位:
BIOCHEMICAL AND HISTOCHEMICAL EXAMINATIONS ON LIPID-BINDING PROTEINS IN RAT AND HUMAN KIDNEY
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批准号:09671159
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.73万
-
财政年份:1997
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负责人:KIMURA Hideki
-
依托单位:
Immunotherapy of lung cancer using biotechnological methods.
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批准号:01480338
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.16万
-
财政年份:1989
-
负责人:KIMURA Hideki
-
依托单位:
海外基金