Polymer-Supported Chiral Dirhodium(II) Complex for Asymmetric Reactions

(1)含Dr(II)络合物的单体与苯乙烯和柔性交联剂共聚，实现了Rh(II)络合物的高效固定化。(2)聚合物支载的手性氟化Dr(II)络合物催化硅烯醇醚与[N-(2-nitrophenylsulfonyl)imino]phenyliodinane的胺化反应，提供了高产率和高对映体选择性的氨基酮，在固体反应物存在下，由于催化剂容易经受搅拌，可使用20次。(3)在连续流动条件下，聚合物支载的手性氯化Dr(II)络合物促进了分子间的羰基环加成反应。其中获得了高产量以及高水平的对映选择性和成交量。

(1) A highly effective immobilization of Rh(II) complex has been achieved by copolymerization of dirhodium(II) complex-containing monomer with styrene and flexible cross-linker.(2) The polymer-supported chiral fluorinated dirhodium(II) complex catalyzed the amination of silyl enol ethers with [N-(2-nitrophenylsulfonyl)imino]phenyliodinane to provide amino ketones in high yields with high levels of enantioselectivity and could be used up to 20 times as the catalyst readily withstood stirring in the presence of the solid reactant.(3) The polymer-supported chiral chlorinated dirhodium(II) complex promoted intermolecular carbonyl ylide cycloaddition reactions in CF3C6H5 under continuous flow conditions, where high yields as well as high levels of enantioselectivity and turnover number were achieved.