Interdisciplinary Training in Alcohol Research

摘要/总结 该培训计划的目的是为研究生提供研究技能，以确定 酒精相关的危险因素，通过研究它们在急性和慢性暴露于 酒精在细胞水平，行为实验室动物，和人类主题。培训计划将 强调酒精的细胞和行为药理学培训，其广泛目标是了解 这些急性和慢性反应如何与个人和环境因素联合收割机结合或相互作用， 酒精使用障碍的风险。培训旨在实现三个目标：1）提供强化培训 在酒精研究; 2）促进酒精研究的跨学科和翻译的观点;和3） 发展专业技能，以支持酒精研究领域的职业发展。提案要求 支持五个博士前的任命。这些任命为期两年。培训将 主要在英国的教师和核心设施的研究计划内交付。这包括 培训教师团队的20名研究人员来自六个学术和研究单位的大学 肯塔基州。丰富的环境为转化和多学科的生物行为学提供了机会。 研究培训设施，如：1）药物和酒精研究中心; 2）临床和 转化科学;和3）新兴成人研究中心的物质滥用预防 （SPECIAL）.我们的教师的酒精特定的专业知识和广泛的研究重点，再加上他们的 跨学科研究为实施拟议的T32培训提供了坚实的基础 该计划将加强我们的学生的研究技能，最终目标是产生明亮，富有成效的 科学家能够在病因学，预防和治疗方面取得重大进展和发现， 酒精使用障碍

ABSTRACT/SUMMARY The aim of this training program is to provide graduate students with the research skills to identify alcohol-related risk factors by investigating their expression in response to acute and chronic exposure to alcohol at the cellular level, behaving laboratory animal, and the human subject. The training program will emphasize training in cellular and behavioral pharmacology of alcohol with the broad objective to understand how such acute and chronic reactions combine or interact with personal and environmental factors to confer risk for alcohol use disorders. The training is designed to achieve three objectives: 1) deliver intensive training in alcohol research; 2) foster interdisciplinary and translational perspectives on alcohol research; and 3) develop professional skills to support career development in alcohol research fields. The proposal requests support for five pre-doctoral appointments. The appointments will be for a two-year period. Training will be primarily delivered within the research programs of the faculty and the core facilities at UK. This includes a training faculty team of 20 researchers drawn from six academic and research units of the University of Kentucky. The rich environment provides opportunities for translational and multidisciplinary bio-behavioral research training in facilities such as the: 1) Center on Drug and Alcohol Research; 2) Center for Clinical and Translational Science; and 3) The Substance-abuse Prevention in Emerging Adults Research Center (SPEAR). The alcohol-specific expertise and broad research foci of our faculty, coupled with their interdisciplinary research provides a solid foundation by which implementation of the proposed T32 training program will bolster the research skills of our students for the ultimate goal of producing bright, productive scientists capable of significant developments and discovery in the etiology, prevention, and treatment of alcohol use disorders.