Interdisciplinary Training in Alcohol Research

摘要/摘要 该培训计划的目的是为研究生提供研究技能，以识别 通过研究酒精相关危险因素在急性和慢性接触中的表达 酒精在细胞水平上，表现为实验动物，以及人类受试者。培训计划将 强调酒精的细胞和行为药理学方面的培训，以更广泛的目标了解 这种急性和慢性反应是如何与个人和环境因素相结合或相互作用的 有酒精使用障碍的风险。该培训旨在实现三个目标：1)提供强化培训 在酒精研究方面；2)促进酒精研究的跨学科和翻译观；以及3) 培养专业技能，支持酒精研究领域的职业发展。建议书要求 支持5个博士前预约。这些任命的任期为两年。培训将是 主要在教职员工的研究项目和英国的核心设施内提供。这包括一个 由20名研究人员组成的培训教员团队，他们来自加州大学的六个学术和研究单位 肯塔基州。丰富的环境为翻译和多学科生物行为提供了机会 研究培训设施，如：1)药物和酒精研究中心；2)临床和酒精研究中心 翻译科学；3)新兴成人研究中心的药物滥用预防 (长矛)。我们教员在酒精方面的专业知识和广泛的研究重点，加上他们的 跨学科研究为实施拟议的T32培训提供了坚实的基础 该计划将加强我们的学生的研究技能，最终目标是产生聪明的，多产的 有能力在病因、预防和治疗方面取得重大进展和发现的科学家 酒精使用障碍。

ABSTRACT/SUMMARY The aim of this training program is to provide graduate students with the research skills to identify alcohol-related risk factors by investigating their expression in response to acute and chronic exposure to alcohol at the cellular level, behaving laboratory animal, and the human subject. The training program will emphasize training in cellular and behavioral pharmacology of alcohol with the broad objective to understand how such acute and chronic reactions combine or interact with personal and environmental factors to confer risk for alcohol use disorders. The training is designed to achieve three objectives: 1) deliver intensive training in alcohol research; 2) foster interdisciplinary and translational perspectives on alcohol research; and 3) develop professional skills to support career development in alcohol research fields. The proposal requests support for five pre-doctoral appointments. The appointments will be for a two-year period. Training will be primarily delivered within the research programs of the faculty and the core facilities at UK. This includes a training faculty team of 20 researchers drawn from six academic and research units of the University of Kentucky. The rich environment provides opportunities for translational and multidisciplinary bio-behavioral research training in facilities such as the: 1) Center on Drug and Alcohol Research; 2) Center for Clinical and Translational Science; and 3) The Substance-abuse Prevention in Emerging Adults Research Center (SPEAR). The alcohol-specific expertise and broad research foci of our faculty, coupled with their interdisciplinary research provides a solid foundation by which implementation of the proposed T32 training program will bolster the research skills of our students for the ultimate goal of producing bright, productive scientists capable of significant developments and discovery in the etiology, prevention, and treatment of alcohol use disorders.