Biobehavioral Research Training Program in Symptom Science

症状科学生物行为研究培训项目

• 批准号: 10166235
• 负责人: CHRISTINE A. MIASKOWSKI
• 金额: $ 9.52万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10166235
• 关键词: Research Training; Training Programs; biobehavior; symptom science

Project Summary The science underlying symptom etiology, the symptom experience, and symptom management has advanced substantially over the last few decades. Yet little is known about the biobehavioral underpinnings of many symptoms or the ways in which biological and behavioral factors interact during the symptom experience. Even less is known about symptom management strategies that can effectively target both biological and behavioral components of the symptom response. Genomics represents an essential focus for the advancement of biobehavioral symptom science and for provision of nursing care that is individualized to the precise needs of patients. There has been growing recognition of the critical role that genomics will play in enabling effective assessment and management of symptoms. The purpose of this supplement is to prepare two predoctoral nursing students to conduct genomic research in symptom science, and to augment the genomics content in an existing training program that is preparing nurse scientists for biobehavioral research careers in symptom science. Upon completion of the program, trainees will have the knowledge and skills necessary to: 1) design and conduct genomic research on symptoms and health-related outcomes, 2) employ multi-method, genomic approaches to the study of symptoms and the testing of symptom management strategies, and 3) translate genomic research findings into recommendations for symptom prevention, assessment and management. The predoctoral curriculum includes standard PhD requirements at UCSF School of Nursing, 3 symptom-specific courses, 4 courses addressing genomics (candidate gene analysis, analysis and interpretation of gene expression data, use of non-invasive biospecimens for analysis of DNA markers, ethical considerations in genomic and genetic research), and a research residency in a genomics laboratory. The interdisciplinary faculty group has significant expertise in genomics and symptom science, including six faculty in the School of Nursing and six affiliated faculty from the School of Medicine at UCSF. Preparing nurse scholars to advance symptom science through rigorous research training in genomic research is essential for improved understanding of the symptom experience and better management of symptoms by patients and clinicians. The UCSF School of Nursing is in a unique position to provide genomic training in symptom science because of its strong research programs in the field, its history of successful research training, and its ongoing collaboration with other Departments, Centers and Institutes at UCSF that are involved in both genomic and symptom-related research.

项目摘要 症状病因学、症状体验和症状管理的科学基础 在过去的几十年里有了很大的进步。然而，人们对生物行为知之甚少。 许多症状的基础或生物和行为因素相互作用的方式 在症状体验过程中。对于症状管理策略更是知之甚少 这可以有效地针对症状反应的生物和行为成分。 基因组学是推进生物行为症状科学的一个重要焦点 并提供个性化的护理，以满足患者的确切需求。那里 越来越多的人认识到基因组学将在使有效 症状的评估和管理。本补编的目的是准备两份 护理博士前学生在症状科学方面进行基因组研究，并加强 现有培训计划中的基因组学内容正在为护士科学家做准备 生物行为研究的职业是症状科学。项目结束后，学员们 将拥有必要的知识和技能：1)设计和进行基因组研究 症状和健康相关结果，2)使用多种方法，基因组方法来 症状研究和症状管理策略测试；3)翻译 基因组研究结果纳入症状预防、评估和治疗建议 管理层。博士前课程包括加州大学旧金山分校的标准博士要求 护理，3个针对症状的课程，4个涉及基因组学的课程(候选基因 基因表达数据的分析、分析和解释，非侵入性生物标本的使用 用于DNA标记的分析，基因组和遗传研究中的伦理考虑)，以及 在基因组实验室做研究驻院医生。跨学科的教职员工群体具有重要的 基因组学和症状科学方面的专业知识，包括护理学院的六名教员 加州大学旧金山分校医学院的六名附属教员。为护士学者的晋升做好准备 症状科学通过严格的研究培训在基因组研究中是必不可少的 通过以下方式提高对症状体验的理解并更好地管理症状 病人和临床医生。加州大学旧金山分校护理学院在提供基因组方面具有独特的地位 症状科学培训由于其在该领域的强大研究计划，其历史 成功的研究培训，以及与其他部门、中心和 加州大学旧金山分校参与基因组和症状相关研究的研究所。