Dissemination and Coordinating Center for the SCGE Consortium

NIH共同基金的体细胞基因组编辑（SCGE）计划的目标是 先进的技术和模型，将导致基因组编辑转化为 临床创造新的治疗策略，用于治疗罕见遗传病患者， 和那些患有常见疾病的人。SCGE传播和协调中心（DCC） 将作为中心，促进这些新的战略和技术的设计，测试， 实施治疗这些疾病的方法。SCGE DCC将支持SCGE 联合会成员和工作与所有团体合作，以促进他们的科学 努力为了实现这一目标，DCC将1）开发通信模式， 项目交互，2）建立管道和流程来收集、集成和分发数据 通过SCGE工具包，以及3）加速小组之间的互动和合作 专注于开发和测试新方法。DCC将创建基础设施， 专家咨询小组项目之间的信息交流，以促进侧重于发展的伙伴关系， 测试和验证解决遗传性疾病并快速传播的新策略 从SCGE到更广泛的科学界的知识。为了实现这一目标， DCC将在NIH SCGE工作组和 项目负责人，协调联合体和小组委员会的定期会议，建立项目 管理基础设施，建立一个工具包来传播成果，跟踪SCGE联盟 库存，管理协作机会基金，以支持SCGE联盟内部 伙伴关系，并开发教育材料。DCC团队将促进行政 活动，以确保科学发现和整个计划是成功的。

The goal of the NIH Common Fund's Somatic Cell Genome Editing (SCGE) program is to advance technologies and models that will lead to the translation of genome editing into the clinic to create new therapeutic strategies for treating both patients with rare genetic diseases, and those with common diseases. The SCGE Dissemination and Coordinating Center (DCC) will serve as the hub to promote these novel strategies and technologies to design, test, and implement approaches to treat these diseases. The SCGE DCC will support the SCGE Consortium members and work cooperatively with all groups to facilitate their scientific endeavors. To accomplish this goal, the DCC will 1) develop modes of communication for project interaction, 2) build pipelines and processes to collect, integrate, and distribute data through the SCGE Toolkit, and 3) accelerate interactions and collaborations among the groups focused on developing and testing new approaches. The DCC will create the infrastructure for information transfer among SCGE projects, to promote partnerships focused on developing, testing, and validating novel strategies to resolve genetic disorders, and to rapidly disseminate the knowledge from the SCGE to the broader scientific community. To achieve this goal, the DCC will develop a communication structure among the NIH SCGE Working Group and the project leaders, coordinate regular meetings for consortium and subcommittees, build a project management infrastructure, establish a Toolkit to disseminate results, track SCGE Consortium inventory, manage the Collaboration Opportunity Fund to support the SCGE intra-consortium partnerships, and develop educational materials. The DCC team will facilitate the administrative activities to ensure that the scientific discoveries and overall program are successful.