Core-007

创建一个学习健康系统（LHS），克服临床护理和 研究需要大量的学习和变革。我们开发了广泛的，世界公认的 在卫生系统改革方面的专业知识和能力，并已表明，一个网络组织 模型来创建LHS工程规模。我们的目标是开发和测试干预措施， 在我们的学术健康中心（AHC）内出现了两个试点LHS。我们会致力达致两个具体目标：1） 让利益相关者参与共同设计和合作测试干预措施，以促进LHS的出现 通过将临床/转化研究与医疗实践相结合来改善结果; 2）制定一个 协作实验室，通过以下方式进一步推进网络化组织实例化的最佳实践 调整和整合现有临床和转化科学与培训中心的职能 （CCTST）核心。由于拟议的努力，我们希望有一个可复制的，经过测试的方法， 促进大型强子对撞机、劳动力、科学和信息学的出现 基础设施，使CCTST能够作为一个学习系统，在AHC和整个 CTSA网络。这是重要的，因为它将进一步推进知识，如何加快 将研究成果转化为更好的成果，为我们地区和全世界带来更好的护理和健康， 民族

Creating a Learning Health System (LHS) that overcomes the artificial barriers between clinical care and research will require significant learning and change. We have developed extensive, world recognized expertise and capacity in health system transformation and have demonstrated that a network organizational model to create LHSs works at scale. Our objective is to develop and test interventions that facilitate the emergence of two pilot LHSs within our Academic Health Center (AHC). We will pursue two specific aims to: 1) engage stakeholders in co-designing and collaboratively testing interventions to facilitate emergence of LHSs that improve outcomes by integrating clinical/translational research with health care practice; and 2) develop a collaborative laboratory to further advance best practices for instantiating the networked organization by aligning and integrating functions across existing Center for Clinical and Translational Science and Training (CCTST) Cores. As a result of the proposed effort, we expect to have a replicable, tested approach to facilitating the emergence of LHSs within the AHC, as well as workforce, scientific, and informatics infrastructure to enable the CCTST to function as a learning system to pursue this work at the AHC and across the CTSA network. This is significant because it will further advance knowledge for how to accelerate the translation of research into improved outcomes and lead to better care and health for our region and the nation.