Core-001

核心001

• 批准号: 10409665
• 负责人: JAMES E. HEUBI
• 金额: $ 59.29万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10409665
• 关键词: Address; Basic Science; Clinical; Clinical Sciences; Communities; Data; Data Aggregation; Data Analyses; Development; Engineering; Health; Health Care Research; Healthcare; Healthcare Systems; Informatics; Knowledge; Learning; Medical center; Participant; Pediatric Hospitals; Persons; Policies; Procedures; Research; Source; System; Technology; Training; Translational Research; Universities; clinical center; data infrastructure; improved; innovation; interoperability; knowledge translation; literacy; literate; operation; programs

The ability to generate, share, and analyze data is fundamental to the operation of the Center for Clinical and Translational Science and Training (CCTST) and participation in wider CTSA networks. Effective fulfillment of these principles requires robust data infrastructure and well-formulated policies and procedures, but more importantly, the development of a highly participatory, informatics- and data-literate research community that embraces best practices alongside innovation. We believe that fulfillment of these data-centric objectives will allow greater discovery, inference, understanding, and translation of knowledge for improved health and wellness. To achieve these objectives, we will focus on the development and implementation of disciplinebased local learning systems to improve data aggregation, data utilization, and informatics literacy, with a focus on our own health care systems [University of Cincinnati (UC) Health and Cincinnati Children’s Hospital Medical Center]. We expect to identify, aggregate, uniformly represent, and make interoperable health care data from a variety of basic and translational science realms, clinical systems, and community sources. We also expect to broadly provide the means for all Cincinnati stakeholders to more effectively access and utilize these biomedical data, and to widely disseminate knowledge derived from such data that is relevant to improving health and health care. Finally, we expect to maximally increase literacy for understanding and using informatics approaches for all Cincinnati stakeholders, to enable our workforce and community to best utilize data for improving health and health care. The resulting programs will be accessible across our spectrum of stakeholders, and their products will be available to all community and CTSA participants. These programs will leverage existing data, technology, and people, and the programs will logically organize and build upon these components to synergistically and continually identify new data, analysis, and technology needs, and to cocreate new informatics solutions for our health care research concentrations. We will be building on our past accomplishments to strengthen this construct and address the challenges of efficient, universal access to biomedical data for knowledge engineering and application.

生成、共享和分析数据的能力是临床和医学中心运营的基础， 翻译科学与培训（CCTST）和参与更广泛的CTSA网络。有效履行 这些原则需要强大的数据基础设施和精心制定的政策和程序，但 重要的是，发展一个高度参与性的、信息学和数据素养的研究社区， 拥抱最佳实践与创新。我们相信，实现这些以数据为中心的目标将 允许更多的发现，推理，理解和翻译知识，以改善健康， 健康为了实现这些目标，我们将重点发展和实施基于学科的 地方学习系统，以改善数据汇总，数据利用和信息素养， 专注于我们自己的医疗保健系统[辛辛那提大学（UC）健康和辛辛那提儿童医院 医疗中心）。我们希望能够识别、聚合、统一表示并实现可互操作的医疗保健 来自各种基础和转化科学领域、临床系统和社区来源的数据。我们 我还希望广泛地为所有辛辛那提利益相关者提供更有效地访问和利用的手段 这些生物医学数据，并广泛传播来自这些数据的知识， 改善健康和保健。最后，我们期望最大限度地提高理解和使用的识字率 所有辛辛那提利益相关者的信息学方法，使我们的劳动力和社区能够最好地利用 改善健康和医疗保健的数据。由此产生的程序将在我们的频谱访问， 利益相关者及其产品将提供给所有社区和CTSA参与者。这些程序将 充分利用现有的数据、技术和人员，项目将在这些基础上进行逻辑组织和构建 组件，以协同和持续地确定新的数据，分析和技术需求，并共同创造 新的信息学解决方案，为我们的医疗保健研究的浓度。我们将在过去的基础上 取得的成就，以加强这一结构，并应对有效、普遍获得 知识工程和应用的生物医学数据。