Core-003

核心003

• 批准号: 10409667
• 负责人: JAMES E. HEUBI
• 金额: $ 48.8万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10409667
• 关键词: Basic Science; Biological Markers; Clinical; Clinical Data; Clinical Investigator; Clinical Research; Clinical Sciences; Collaborations; Communities; Data; Dental; Development; Diagnostic tests; Discipline of Nursing; Disease; Faculty; Funding Opportunities; Future; Goals; Health; Health Occupations; High School Student; Institution; Intervention; Laboratories; Medical; Methods; Pilot Projects; Process; Program Development; Research; Research Personnel; Resources; Science; Students; Training; Training Programs; Translational Research; Translations; Universities; Workforce Development; acute care; base; career; clinical center; community engaged research; data dissemination; data management; design; health equity; high school; innovation; member; multidisciplinary; novel; programs; success; training opportunity; translational pipeline; translational scientist; translational study; undergraduate student

The University of Cincinnati’s Center for Clinical and Translational Science and Training (CCTST) is dedicated to providing all current and future members of the clinical and translational science workforce within our institution, community, and beyond with state-of-the-science educational opportunities. To accomplish this endeavor, we propose to further develop our Translational Workforce Development (TWD) program to provide training for early-stage, mid-career, and established investigators; boots-on-the-ground clinical research professionals; pre-professional trainees (allied health, pre-medical, nursing, dental, and medical assistants); and innovatively, community residents and high school students. Specifically, we will: 1) create new opportunities for formal training in community-engaged research for health equity, translational regulatory science, and acute care research; 2) develop a comprehensive training program for clinical research professionals to enhance the clinical research workforce, emphasizing a team-based approach; 3) expand and diversify the pipeline of translational researchers by exposing early-stage students (high school, allied health associate students, undergraduate health professions) to clinical research using existing and proposed community-engaged programs; and 4) design training for high-quality clinical data management and dissemination. To further support the workforce and development of translational research initiatives, the Pilot Translational and Clinical Studies Program (PTC) provides the means for junior and established basic science and clinical investigators to engage in multidisciplinary and collaborative team science approaches, develop efficient methods and processes, and generate robust preliminary data necessary for large-scale funding opportunities. The overall goal of the PTC is to accelerate the development of novel disease biomarkers, diagnostic tests, and therapies by facilitating translation of basic science laboratory discoveries across the Academic Health Center into novel clinical approaches and interventions. To build on the PTC’s success, we will innovatively expand the program by facilitating novel pilot translational and clinical studies through promotion of interdisciplinary and community collaboration and provide mechanisms for junior faculty to increase independence by providing active investigator assistance and a robust portfolio of pilot project mechanisms. Specifically, we will: 1) provide a comprehensive pilot project portfolio, including team-based and community-engaged support programs and resources, to promote collaboration and catalyze advancement of science across the translational research continuum throughout the Academic Health Center and beyond; and 2) develop training opportunities and resources for junior investigators to promote independence in clinical and translational research.

辛辛那提大学的临床和转化科学与培训中心（CCTST）致力于 为我们的临床和转化科学劳动力的所有当前和未来成员提供 机构，社区，和超越国家的科学教育机会。为了实现这一 奋进，我们建议进一步发展我们的翻译劳动力发展（TWD）计划， 为早期、职业中期和已建立的研究者提供培训; 研究专业人员;专业前受训人员（专职保健、医学预科、护理、牙科和医学 助理）;和创新，社区居民和高中生。具体而言，我们将：1）创建 在社区参与的健康公平研究、转化监管研究、 科学和急性护理研究; 2）制定临床研究的综合培训计划 专业人员，以加强临床研究的劳动力，强调以团队为基础的方法; 3）扩大和 通过接触早期学生（高中，专职医疗），使翻译研究人员的渠道多样化 准学生，本科生健康专业），以临床研究使用现有的和拟议的 社区参与计划;以及4）设计高质量临床数据管理培训， 传播。为了进一步支持劳动力和转化研究计划的发展，试点项目 转化和临床研究计划（PTC）提供了初级和既定的基本手段 科学和临床研究者参与多学科和协作团队科学方法， 制定有效的方法和流程，并生成大规模评估所需的可靠的初步数据。 融资机会。PTC的总体目标是加速新疾病的发展 生物标志物，诊断测试和治疗，通过促进基础科学实验室发现的翻译 整个学术健康中心进入新的临床方法和干预措施。在PTC的基础上， 成功后，我们将通过促进新的试点转化和临床研究，创新性地扩大该计划 通过促进跨学科和社区合作，并为初级教师提供机制 通过提供积极的调查协助和一系列强有力的试点项目， 机制等具体而言，我们将：1）提供全面的试点项目组合，包括以团队为基础的 社区参与的支持计划和资源，以促进合作和催化进步， 整个学术健康中心及其他领域的转化研究连续体的科学; 2)为初级研究者开发培训机会和资源，以促进临床和 翻译研究