Cincinnati Center for Clinical and Translational Sciences and Training

辛辛那提临床和转化科学与培训中心

• 批准号: 9261619
• 负责人: JAMES E. HEUBI
• 金额: $ 341.94万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9261619
• 关键词: Acute; Adult; Age; Caring; Child; Clinical; Clinical Informatics; Clinical Research; Clinical Sciences; Clinical Trials; Clinical effectiveness; Collaborations; Communities; Development; Discipline; Education; Educational process of instructing; Elderly; Environment; Environmental Exposure; Environmental Health; Ethics; Family; Fostering; Future; Goals; Government Officials; Health; Healthcare; Informatics; Information Technology; Learning; Longevity; Master of Science; Methods; Multicenter Trials; Participant; Patients; Performance; Population; Process; Provider; Race; Recruitment Activity; Research; Research Methodology; Research Personnel; Science; Scientist; Services; Site; Training; Translational Research; Trust; Underrepresented Minority; Universities; Vision; Work; base; biomedical informatics; career development; data integration; design; health care delivery; health disparity; improved; innovation; medical specialties; member; named group; next generation; patient oriented research; practice-based research network; programs; sex; success

The vision of the Center for Clinical and Translational Science and Training (CCTST) at the University of Cincinnati is to be the Greater Cincinnati portal of entry for support of clinical and translational research with a goal to enfranchise stakeholders from a broad base to integrate research into healthcare delivery, improve community wellness, foster effective, efficient multisite trials, and train the clinical and translational research workforce of the future. We will realize this vision through three aims: (1) Empower stakeholders in the process of integrating research with healthcare practice and community wellness, (2) Create the workforce of the future, and (3) Optimize efficiency and effectiveness of clinical research. Building on the successes of the last 6 years, we propose innovative changes to existing programs and creation of new programs designed to provide support for high quality cutting-edge research done by teams of scientists. Building on our existing programs, we propose to (1) provide innovative programs in career development for a wide range of learners, (2) develop new pilot programs to support creation of solutions for obstacles to research, (3) expand our community engagement program to extend beyond Greater Cincinnati to stakeholders across the U.S., (4) provide more comprehensive support by biomedical informatics for the services provided by the CCTST, (5) expand support for patient-oriented research, and (6) help overcome regulatory and ethical challenges that impede clinical research in local and multisite studies. We propose innovative efforts directed toward fostering learning health networks and creating a Research Commons to provide more comprehensive support to investigators. We will focus on (1) teaching and implementing team science principles and encouraging collaboration across a variety of disciplines and stakeholders, (2) consolidation of clinical trials support across the academic health center by creating Cinci-HERO to help multicenter trials for which the CCTST affiliates are the leads (including serving as the IRB of record) or site participants and recruitment of populations across the lifespan including underrepresented minorities, those with environmental exposures and health disparities, and (3) acute care research and lifespan data integration that takes advantage of institutional strengths.

临床和转化科学与培训中心（CCTST）的愿景 辛辛那提大学将成为大辛辛那提的入口，以支持临床和 翻译研究的目标是从广泛的基础上赋予利益相关者整合 研究医疗保健服务，改善社区健康，促进有效，高效 多中心试验，并培训未来的临床和转化研究人员。我们将 通过三个目标实现这一愿景：（1）在整合过程中赋予利益相关者权力 研究与医疗保健实践和社区健康，（2）创造劳动力的 （3）优化临床研究的效率和效果。基础上 过去6年的成功，我们提出了创新的变化，现有的计划和创造 旨在为高质量的尖端研究提供支持的新计划， 科学家团队。在现有项目的基础上，我们建议（1）提供创新的 为广泛的学习者提供职业发展方案，（2）开发新的试点方案， 支持为研究障碍创造解决方案，（3）扩大我们的社区参与 该计划将从大辛辛那提扩展到美国各地的利益相关者，(4)提供更多 生物医学信息学为CCTST提供的服务提供全面支持，（5） 扩大对以患者为导向的研究的支持，以及（6）帮助克服监管和道德问题 阻碍本地和多中心临床研究的挑战。我们提出创新 致力于促进学习健康网络和创建一个研究共享， 为调查人员提供更全面的支持。我们将专注于（1）教学和 实施团队科学原则，并鼓励各种合作 学科和利益相关者，（2）整合学术界的临床试验支持 通过创建Cinci-HERO来帮助CCTST附属机构的多中心试验， 是负责人（包括作为记录的IRB）或研究中心参与者， 包括代表性不足的少数群体， 环境暴露和健康差异，以及（3）急性护理研究和寿命数据 利用体制优势的一体化。