Training Program in Translational Research

转化研究培训计划

• 批准号: 10415974
• 负责人: ANDREW P LIEBERMAN
• 金额: $ 31.22万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10415974
• 关键词: Training Programs; Translational Research

Abstract The Training Program in Translational Research offers an interdisciplinary program of study and research that prepares graduate students for successful careers at the interface between basic biomedical science and clinical medicine. This program is designed for predoctoral Ph.D. students and aims to address the widely-recognized shortage of rigorously trained scientists who can successfully work together with medical professionals to bridge the gap between basic science and clinical practice. Annual support for 6 trainees (3 in their 2nd year and 3 in 3rd year of graduate studies) is requested throughout five years of funding. The program is centered in the University of Michigan School of Medicine, with participating faculty members affiliated with ten departments (6 clinical and 4 basic science) providing multidisciplinary training for graduate students in 15 degree-granting programs. Additional faculty mentors have their primary appointments in the College of Pharmacy, the School of Dentistry and the College of LSA. These faculty members were selected because of their commitment to graduate education and expertise in translational research. Based on the long-standing research interests of these preceptors, scientific projects will be focused on areas of excellence in cancer biology, epigenetics, aging, immunology, neuroscience, omics studies, precision medicine and experimental therapeutics & biomarkers. This broad spectrum of research activities provides a wide-range of exciting opportunities for students to work on translational research projects. The educational experience will be enhanced and supported by integration of dual-mentors with corresponding expertise in the basic and clinical aspects of the research project. The curriculum includes innovative, individualized and competency-based coursework in translational science, training in the performance of rigorous and reproducible research, and participation in clinical rotations, interdisciplinary conferences, tumor boards, and grand rounds. These activities will be complemented by a T32- based seminar series, workshops, annual retreat, and career development support. Our goal is to foster the training of basic researchers who will interact with clinicians and laboratory professionals to become future leaders in translating research findings into clinical practice to improve patient outcomes. The program will be administered by co-directors who are experienced in, and passionate about, graduate student education and translational research. The program will benefit from the advice and oversight of internal and external advisory committees, both of which will assist the co-directors in running and evaluating the program. Graduates from this program will have the skills and knowledge to undertake independent careers that feature translational and multidisciplinary research. In summary, the strengths of this training program are the direct link between the basic and clinical sciences, the collegial and successful preceptors, the experienced program leadership, and the rich academic research and clinical environment at the University of Michigan.

摘要 翻译研究培训计划提供跨学科的学习和研究计划， 为研究生在基础生物医学科学和临床之间的成功职业生涯做好准备 医药。该项目是为博士前博士生设计的，旨在解决被广泛认可的 缺乏训练有素的科学家，他们可以成功地与医学专业人员合作，架起桥梁 基础科学与临床实践之间的差距。每年向6名学员提供支助(2年级3名，3年级3名 在整个五年的资助期间，都要求提供研究生课程(研究生学习年度)。该项目以该大学为中心 密歇根医学院，有参与的教职员工隶属于十个系(6个临床和 4基础科学)为15个学位授予项目的研究生提供多学科培训。 更多的教师导师在药学院、牙科学院担任主要职务 和LSA学院。这些教职员工之所以被选中，是因为他们致力于毕业 翻译研究方面的教育和专业知识。基于这些长期的研究兴趣 教授，科学项目将集中在癌症生物学，表观遗传学，老龄化， 免疫学、神经科学、组学研究、精确医学和实验治疗学及生物标志物。这 广泛的研究活动为学生提供了广泛的令人兴奋的工作机会 翻译研究项目。教育体验将通过整合 在研究项目的基础和临床方面具有相应专业知识的双重导师。这个 课程包括翻译科学方面的创新、个性化和基于能力的课程工作， 开展严谨和可重复的研究以及参与临床轮换方面的培训； 跨学科会议、肿瘤委员会和盛大的巡回会议。这些活动将由一架T32- 以系列研讨会、研讨会、年度静修和职业发展支持为基础。我们的目标是培养 培训基础研究人员，他们将与临床医生和实验室专业人员互动，成为未来 将研究成果转化为临床实践以改善患者结果的领导者。该计划将是 由在研究生教育方面经验丰富并充满热情的联席董事管理 翻译研究。该方案将受益于内部和外部咨询的咨询和监督 委员会，这两个委员会都将协助联席主任运行和评估该计划。从这里毕业的学生 该计划将拥有从事独立职业的技能和知识，这些职业以翻译和 多学科研究。总而言之，这一培训计划的优势是将 基础和临床科学，合议性和成功的导师，经验丰富的项目领导，以及 密歇根大学丰富的学术研究和临床环境。