Training Program in Translational Research

转化研究培训计划

• 批准号: 10618868
• 负责人: ANDREW P LIEBERMAN
• 金额: $ 31.83万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10618868
• 关键词: Training Programs; Translational Research

Abstract The Training Program in Translational Research offers an interdisciplinary program of study and research that prepares graduate students for successful careers at the interface between basic biomedical science and clinical medicine. This program is designed for predoctoral Ph.D. students and aims to address the widely-recognized shortage of rigorously trained scientists who can successfully work together with medical professionals to bridge the gap between basic science and clinical practice. Annual support for 6 trainees (3 in their 2nd year and 3 in 3rd year of graduate studies) is requested throughout five years of funding. The program is centered in the University of Michigan School of Medicine, with participating faculty members affiliated with ten departments (6 clinical and 4 basic science) providing multidisciplinary training for graduate students in 15 degree-granting programs. Additional faculty mentors have their primary appointments in the College of Pharmacy, the School of Dentistry and the College of LSA. These faculty members were selected because of their commitment to graduate education and expertise in translational research. Based on the long-standing research interests of these preceptors, scientific projects will be focused on areas of excellence in cancer biology, epigenetics, aging, immunology, neuroscience, omics studies, precision medicine and experimental therapeutics & biomarkers. This broad spectrum of research activities provides a wide-range of exciting opportunities for students to work on translational research projects. The educational experience will be enhanced and supported by integration of dual-mentors with corresponding expertise in the basic and clinical aspects of the research project. The curriculum includes innovative, individualized and competency-based coursework in translational science, training in the performance of rigorous and reproducible research, and participation in clinical rotations, interdisciplinary conferences, tumor boards, and grand rounds. These activities will be complemented by a T32- based seminar series, workshops, annual retreat, and career development support. Our goal is to foster the training of basic researchers who will interact with clinicians and laboratory professionals to become future leaders in translating research findings into clinical practice to improve patient outcomes. The program will be administered by co-directors who are experienced in, and passionate about, graduate student education and translational research. The program will benefit from the advice and oversight of internal and external advisory committees, both of which will assist the co-directors in running and evaluating the program. Graduates from this program will have the skills and knowledge to undertake independent careers that feature translational and multidisciplinary research. In summary, the strengths of this training program are the direct link between the basic and clinical sciences, the collegial and successful preceptors, the experienced program leadership, and the rich academic research and clinical environment at the University of Michigan.

抽象的 转化研究培训计划提供跨学科的学习和研究计划， 为研究生在基础生物医学科学和临床之间的交叉领域取得成功的职业生涯做好准备 药品。该计划是为博士前博士设计的。学生，旨在解决广泛认可的问题 缺乏训练有素的科学家能够成功地与医疗专业人员合作，以弥合问题 基础科学与临床实践之间的差距。每年为 6 名学员提供支持（第二年 3 名，第三年 3 名） 研究生学习年）要求在整个五年的资助期间。该计划以大学为中心 密歇根医学院的 10 个系（6 个临床和 4基础科学）为研究生提供15个学位授予项目的多学科培训。 其他教师导师的主要任命是在药学院、牙科学院 和 LSA 学院。这些教师之所以被选中是因为他们致力于毕业 转化研究方面的教育和专业知识。基于这些人长期的研究兴趣 导师们，科学项目将重点关注癌症生物学、表观遗传学、衰老、 免疫学、神经科学、组学研究、精准医学以及实验疗法和生物标志物。这 广泛的研究活动为学生提供了广泛的令人兴奋的工作机会 转化研究项目。教育经验将通过整合得到增强和支持 在研究项目的基础和临床方面具有相应专业知识的双导师。这 课程包括转化科学方面的创新、个性化和基于能力的课程， 进行严格且可重复的研究以及参与临床轮转的培训， 跨学科会议、肿瘤委员会和大型查房。这些活动将得到 T32-的补充 基于研讨会系列、讲习班、年度务虚会和职业发展支持。我们的目标是培养 培训基础研究人员，他们将与临床医生和实验室专业人员互动，成为未来的基础研究人员 将研究成果转化为临床实践以改善患者治疗效果的领导者。该计划将是 由在研究生教育方面经验丰富且充满热情的联合主任管理 转化研究。该计划将受益于内部和外部咨询的建议和监督 委员会，这两个委员会将协助联合主任运行和评估该计划。从此毕业 计划将具备从事独立职业的技能和知识，这些职业以翻译和 多学科研究。总之，该培训计划的优势在于将以下方面直接联系起来： 基础科学和临床科学、大学和成功的导师、经验丰富的项目领导，以及 密歇根大学丰富的学术研究和临床环境。