Predoctoral Training at the Interface Chemistry and Biology

要求提供支助，以继续执行已证明非常成功的培训方案， 在化学和生物学的交界处的博士预科生。在过去的15年里，这个CBI 培训计划支持了66名研究生，其中8人随后获得了NSF， 凯克基金会、国防科学与工程研究生（NDSEG）或美国癌症 社会博士预科奖学金。此外，耶鲁大学有意识地努力提高其 通过在初级和高级职位上的新聘用和晋升， 在分子，细胞和发育生物学（MCDB），化学，和 分子生物物理学和生物化学（MB&B）。此外，耶鲁大学对前者的收购 拜耳制药在邻近的西黑文的研发基地允许推出化学生物学 研究所，这将最终容纳9个额外的教师在化学/生物学接口工作。 考虑到教师的这种扩张，需要额外的资金来支持总共12个CBI的博士前 实习生 所有被录取的学员都至少拥有相关领域的学士学位，并通过 申请化学系或耶鲁生物和生物医学科学（BBS） 程序.无论进入模式，所有学员都有一个共同的第一年经验， 跨学科的课程工作，实验室轮换，以及密切的监督和指导，从 研究生主任与执行委员会一起。在第一年结束时， 学员从27名CBI培训师中选择一名论文导师，开始密集的研究， 在第二年增加课程。学生在第二年和第三年获得该补助金的支持， 他们的博士训练。所有学生至少教一年，以帮助他们作为教师学者的培训。 增加少数民族受训人数和提供道德问题教育的方案 与研究有关的知识是这项培训计划的重要组成部分。 培训计划的特点包括跨部门的课程工作，包括特别 为新学员设计的课程，严格的部门间轮换时间表， 学员将在耶鲁大学三个实验室体验科学，这是一个每月一次的内部研讨会项目， 讨论最近的结果，化学生物学秋季务虚会和一个非常成功的年度化学 生物研讨会与CBI实习生海报比赛。

Support is requested to continue what has proven to be a highly successful program for the training of predoctoral students at the interface of chemistry and biology. Over the past fifteen years, this CBI training program has supported 66 graduate students, eight of which have subsequently received NSF, Keck Foundation, National Defense Science and Engineering Graduate (NDSEG) or American Cancer Society predoctoral fellowships. In addition, Yale has made a conscious effort to increase its representation in this interdisciplinary area through new hires and promotions at the junior and senior levels in the departments of Molecular, Cellular and Developmental Biology (MCDB), Chemistry, and Molecular Biophysics and Biochemistry (MB&B). Moreover, Yale University’s acquisition of the former Bayer Pharmaceuticals R&D site in neighboring West Haven allowed the launch a Chemical Biology Institute, which will ultimately house 9 additional faculty working at the chemistry/biology interface. Given this expansion of faculty, additional funds are requested to support a total of 12 CBI predoctoral trainees. All trainees admitted to the program have at least a Bachelor’s degree in a relevant field and enter via application to the Chemistry department or to the Yale Biological and Biomedical Sciences (BBS) program. Regardless of mode of entry all trainees share a common first year experience involving interdisciplinary course work, laboratory rotations, as well as close supervision and guidance from the Director of Graduate Students in conjunction with the Executive Committee. At the end of their first year, trainees chose a thesis advisor from among the 27 CBI trainers and begin intensive research with additional courses in their second year. Students are supported on this grant in years two and three of their doctoral training. All students teach for at least one year to aid in their training as teacher-scholars. Programs for increasing the number of minority trainees and for providing education in ethical issues related to research represent important parts of this training program. Special features of the training program include interdepartmental course work, including specially designed courses for the new trainees, a rigorous interdepartmental rotation schedule during which the trainee will experience science in three laboratories at Yale, a monthly in-house seminar program for discussion of recent results, Chemical Biology Fall Retreat and a highly successful annual Chemical Biology Symposium with a CBI Trainee Poster competition.