Metabolomics Core

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PROJECT SUMMARY/ABSTRACT – Metabolomics Core The goals of the Metabolomics Core (MC) remain to advance the understanding of metabolism and metabolic flux in relation to iron, heme, hematopoeisis and red cell biology through the use of cutting edge technology, newly developed methodologies and Bioinformatic analyses. The need for the MC continues to expand as the applicability of this technology to model systems is further realized. Our MC core, which has been in existence for over 15 years, has rapidly evolved to meet user demand including the development of extensive education (workshops), which are made available to all users through the CIHD Enrichment activities, high throughput sample processing, improve flux analysis and utilization of bioinformatic tools to process data and interpret results. We have increased personnel focused on metabolomics, lipidomics and bioinformatics as well as adding cutting edge instrumentation (e.g. high resolution orbitrap instrument) to satisfy the demand for high end isotope tracer and flux analysis. The Core will continue to refine its methodologies, standardize reporting using developed custom data analysis reporting software and provide educational opportunities for successful investigator-initiated research and advancement.