Core A: Administrative Core

摘要 应激、创伤和复原力管理核心(STAR)将发展、支持和 通过提供科学的领导、行政的支持和科学的事业来指导中心 开展活动，确保初级调查人员取得成功，并建立一个跨学科中心，以 促进我们对压力、创伤和创伤的风险机制和干预途径的理解 逆境。明星科布雷将建立一个领导团队，负责监督和 沟通STAR COBRE活动以确保中心的成功和可持续发展。这个 行政核心将由斯特劳德博士领导，斯特劳德博士是一位成就卓著的领导人，在 胎儿/婴儿和青少年/青春期风险和弹性的神经生物学和行为标记物 过渡，以及长期成功的导师关系。副主任蒂尔卡博士是一位学术精神病学家 具有童年逆境和两个孩子的风险的分子和行为基础方面的专业知识 和成年人，以及多年成功的研究指导和领导经验，包括担任 R25科研培训计划。由NIH资助的调查人员组成的执行委员会，有出色的跟踪记录 在压力、创伤和心理创伤领域的领导、指导和研究成就的记录 Resilience将指导中心。内部咨询委员会(IAC)、外部咨询委员会(EAC)、 和社区咨询委员会(CAB)将就整体Cobre、 单个项目，以及中心可持续发展的努力。一流的辅导和教育 计划，包括密集的R01赠款撰写研讨会和研讨会，将支持职业发展 为初级调查人员提供资金，并确保成功过渡到R01级资金。指导计划的特点是 为每个项目负责人(PL)提供一名专家明星导师和另一名由NIH资助的补充导师， 并将以正式的个人发展计划和导师-学员契约为指导。招聘一名新的 来自代表性不足的种族和/或民族群体的“后起之秀”教员和一个试点项目(PP) 该计划由米里亚姆医院资助，重点是增加多样性和扩大青年干部队伍 研究人员准备进行以压力、创伤和韧性为重点的变革性研究。一个 评估和质量改进计划将利用定量和定性的方法形成 以及对整个方案的总结性评价、核心的有效性和利用率、 委员会、导师和教育方案以及PL研究和职业发展进展，如 以及科布雷成为自给自足的地方资源和领先的国家压力中心的能力， 创伤和恢复力。

ABSTRACT The Administrative Core of the COBRE for stress, trauma, and resilience (STAR) will develop, support, and guide the center by providing scientific leadership, administrative support, and scientific and career development activities to ensure the success of the junior investigators and build a transdisciplinary center to advance our understanding of mechanisms of risk and avenues for intervention for stress, trauma, and adversity. The STAR COBRE will establish a leadership team who will be responsible for oversight and communication of STAR COBRE activities to ensure success and sustainability of the Center. The Administrative Core will be led by Director Dr. Stroud, an accomplished leader with expertise in the neurobiological and behavioral markers of risk and resilience in the fetal/infant and adolescent/pubertal transitions, and a long history of successful mentorship. Deputy Director Dr. Tyrka is an academic psychiatrist with expertise in childhood adversity and the molecular and behavioral underpinnings of risk in both children and adults, and many years of successful research mentoring and leadership experience including as PI of an R25 research training program. An Executive Committee of NIH-funded investigators with an outstanding track record of leadership, mentorship, and research accomplishments in the domain of stress, trauma, and resilience will guide the Center. An Internal Advisory Committee (IAC), External Advisory Committee (EAC), and Community Advisory Board (CAB) will provide advice and ongoing feedback on the overall COBRE, the individual projects, and the efforts towards Center sustainability. A state-of-the-art Mentoring and Educational Program, including an intensive R01 grant writing seminar and workshop, will support the career development of junior investigators and ensure successful transition to R01-level funding. The mentoring program features both an expert STAR mentor and another complementary NIH-funded mentor for each Project Leader (PL), and will be guided by formal individual development plans and mentor-mentee compacts. Recruitment of a new “rising star” faculty member from an under-represented racial and/or ethnic group and a Pilot Project (PP) program, funded by The Miriam Hospital, are focused on increasing diversity and expanding the cadre of junior investigators poised to conduct transformational research focused on stress, trauma, and resilience. An evaluation and quality improvement program will utilize quantitative and qualitative approaches to formative and summative evaluations of the overall program, the effectiveness and utilization of the Cores, the Committees, the Mentorship and Educational Program, and PL research and career development progress, as well as the COBRE’s capacity to become a self-sustaining local resource and leading national center on stress, trauma, and resilience.