Oncology Research Training for Surgeon-Scientists

项目总结 这项申请是对外科科学家的翻译肿瘤学研究培训的竞争性更新， 肯塔基大学(英国)为符合资格的学员设计的变革性培训计划 外科学科，并对肿瘤学研究感兴趣。该计划针对关键的国家 从事癌症研究的外科科学家的数量在两年的时间里下降 密集的跨学科导师研究培训，为学员成为独立科学家做准备 他们已经做好充分准备，将在培训期间学到的最先进的技术融入到 学术研究事业成功。受训人员(每年2名)通常在以下情况下参加培训 完成研究生2年或3年的住院医师培训或完成外科手术 并选择基础科学选项(途径1)或医疗保健提供研究选项 (轨道2)。第1轨道的机会横跨细胞信号、肿瘤生物学、癌症进展和转移，如 以及代谢组学、肿瘤基因组学和表观遗传学等不断发展的领域。轨道2，拟议的新方案 该部门提供癌症差异、实施科学和人口层面调查方面的培训。在……里面 除了密集的研究经验外，受训者还需要完成理学硕士或临床博士学位 和翻译科学，并通过结合进一步发展来补充他们的课程 负责以下领域的正式课程和专业技能发展讲习班和研讨会 进行研究、可再现性、手稿和提案的开发。通过定期安排 研讨会和讲座可通过马基癌症中心、他们的部门和著名的英国 中心，包括临床和翻译科学中心，学员从事丰富的经验和 指导性学习，使他们成为多学科团队类型的积极贡献者 对于复杂癌症患者的最佳治疗是必不可少的。成功完成的要求 硕士或博士学位都会增加这一培训计划的深度和广度，扩大对以下方面的接触 其他在论文委员会任职的英国科学家。初级培训教师由基础和基础培训人员组成。 人口科学家和临床科学家，他们都在跨学科合作；每个主要 教师导师是他或她所在领域内公认的专家，在 培训年轻的调查员。一种“流水线”的导师发展机制使我们能够开发出有前途的 在我们基于团队的指导方法中，职业生涯早期的教职员工作为导师。这个节目，就是 致力于促进外科科学家社区的多样性，包括女性和来自 代表不足的群体，在解决#年令人震惊的下降问题方面取得了非常成功的目标 从事肿瘤学研究的活跃外科医生-科学家的数量。作为一名培训人员，我们 充满激情，积极进取，致力于培养未来的学术外科医生。

PROJECT SUMMARY This application is a competitive renewal of Translational Oncology Research Training for Surgeon Scientists, a transformative training program at the University of Kentucky (UK) designed for qualified trainees in the surgical disciplines and with an interest in oncology research. The program addresses critical national declines in the number of surgeon scientists engaged in cancer research through a two-year period of intensive, interdisciplinary mentored research training to prepare trainees to become independent scientists who are well prepared to incorporate state-of-the-art techniques learned during their training period into a successful academic research career. Trainees (2 each year) typically enter the program following completion of postgraduate year (PGY) 2 or 3 of their residency training or upon completion of the surgical residency and select either the basic science option (Track 1) or the healthcare delivery research option (Track 2). Opportunities in Track 1 span cell signaling, tumor biology, cancer progression and metastasis as well as evolving areas such metabolomics, oncogenomics and epigenetics. Track 2, a proposed new program component, provides training in cancer disparities, implementation science and population-level enquiry. In addition to an intensive research experience, trainees complete a Master of Science or PhD degree in clinical and translational sciences and supplement their coursework with further development through a combination of formal courses and professional skills development workshops and seminars in such areas as responsible conduct of research, reproducibility and manuscript and proposal development. Through regularly scheduled seminars and lectures available through the Markey Cancer Center, their departments and prominent UK centers, including the Center for Clinical and Translational Science, trainees engage in rich experiential and didactic learning that prepares them as active contributors to the types of multidisciplinary teams that are essential for the optimal treatment of the complex cancer patient. The requirement to successfully complete either a master’s or PhD degree adds depth and breadth to this program of training, broadening exposure to other UK scientists serving on thesis committees. The primary training faculty is composed of basic and population scientists and clinician-scientists, all of whom work collaboratively across disciplines; each primary faculty mentor is a recognized expert in his or her field and has a long record of research productivity in the training of young investigators. A “pipeline” mentor development mechanism allows us to develop promising early-career faculty members as mentors within our team-based mentoring approach. This program, which is committed to fostering diversity in the community of surgeon scientists, including women and those from underrepresented groups, has been highly successful in achieving its goals to address alarming declines in the number of active surgeon-scientists conducting oncology research. As a training faculty, we are passionate, motivated and committed to the training of future academic surgeons.