Designing the most effective vehicle to deliver alginate to effectively reduce fat digestion and absorption

肥胖是世界上增长最快的医学问题之一，并迅速成为死亡的主要原因之一。英国每年有337，000人死亡与超重有关，英国在与超重有关的死亡方面领先欧盟。肥胖将成为欧盟未来更大的问题，因为2200万儿童被认为超重或肥胖，每年增加40万。在我们之前由BBSRC资助的研究中，我们证明了藻酸盐（海藻膳食纤维）可以减少脂肪的消化和吸收，因此可以帮助减少肥胖。我们沿着与Gregg的PLC一起开发了一种基于面包的藻酸盐产品，该产品是高度可接受的，没有与肠道相关的副作用。在这里，我们打算通过与公众协商，开发一系列基于藻酸盐的食品，并进行进一步的研究，使我们能够做出健康声明。这将为海藻酸盐产品作为减肥辅助剂进入市场铺平道路。

Obesity is one of the fastest growing medical issues across the world and is fast becoming one of the leading causes of mortality. 337,000 death/year in Britain are related to being overweight and Britain leads EU in deaths related to excess body weight. Obesity will become an even greater problem in the future for the EU as 22 million children are considered overweight or obese, with this increasing by 400,000 every year. In our previous studies funded by BBSRC we demonstrated that alginates (dietary fibres from seaweeds) could reduce fat digestion and absorption, so could help to reduce obesity. We along with Gregg's PLC have developed a bread based alginate product which was highly acceptable with no bowel related side effects. Here we intend to develop a range of alginate based food products driven by consultation with the public and carry out further studies to allow us to make a health claim. This will pave the way for alginate products to come to market as an aid to weight loss.