Designing the most effective vehicle to deliver alginate to effectively reduce fat digestion and absorption

肥胖是世界上增长最快的医疗问题之一，并迅速成为导致死亡的主要原因之一。英国每年有33.7万例死亡与超重有关，英国在欧盟中与超重有关的死亡人数最多。肥胖在未来将成为欧盟的一个更大的问题，因为2200万儿童被认为超重或肥胖，并且每年增加40万。在我们之前由BBSRC资助的研究中，我们证明了海藻酸盐（来自海藻的膳食纤维）可以减少脂肪的消化和吸收，因此可以帮助减少肥胖。我们和Gregg's PLC一起开发了一种基于面包的海藻酸盐产品，这种产品被高度接受，没有肠道相关的副作用。在这里，我们打算通过咨询公众，开发一系列以海藻酸盐为基础的食品，并进行进一步的研究，以使我们能够做出健康声明。这将为海藻酸盐产品作为减肥辅助产品进入市场铺平道路。

Obesity is one of the fastest growing medical issues across the world and is fast becoming one of the leading causes of mortality. 337,000 death/year in Britain are related to being overweight and Britain leads EU in deaths related to excess body weight. Obesity will become an even greater problem in the future for the EU as 22 million children are considered overweight or obese, with this increasing by 400,000 every year. In our previous studies funded by BBSRC we demonstrated that alginates (dietary fibres from seaweeds) could reduce fat digestion and absorption, so could help to reduce obesity. We along with Gregg's PLC have developed a bread based alginate product which was highly acceptable with no bowel related side effects. Here we intend to develop a range of alginate based food products driven by consultation with the public and carry out further studies to allow us to make a health claim. This will pave the way for alginate products to come to market as an aid to weight loss.