课题基金 / 基金详情

RICIN REDUCTION OF MUSCLE FUNCTION

RICIN REDUCTION OF MUSCLE FUNCTION
蓖麻毒素降低肌肉功能
批准号:
3265532
负责人:
ALAN B SCOTT
金额:
$15.02万
依托单位国家:
美国
项目类别:
财政年份:
1989
资助国家:
美国
项目状态:
已结题
起止时间:
1989-08-01 至 1993-07-31

项目摘要

项目成果

ALAN B SCOTT的其他基金

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相关文献

中文摘要
翻译
本项目旨在确定注射的剂量和方法
英文摘要
This project seeks to determine the dose and the method of injection of ricin, which will permanently reduce eyelid and oculo-rotary muscle function in the rabbit without excessive adverse local or systemic side effects. Reduction in muscle size, muscle regeneration, and other effects on the target muscle will be assessed by functional tests and by light and electronmicroscopy. Effect on adjacent tissues will be assessed by clinical examination and by histology. Effects of neuron transport to and within the central nervous system will be assessed by histology. Systemic effects will be monitored by tests of liver, renal and cardiac function and by histology of these organs. If these experiments are successful, this approach and these data will form the basis of an experimental, clinical drug treatment for focal dystonias.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
Preventing ptosis after botulinum treatment.
肉毒杆菌治疗后预防上睑下垂。
DOI: 10.1097/00002341-199706000-00002
发表时间: 1997
期刊: Ophthalmic plastic and reconstructive surgery
影响因子: 2
作者: [Scott,AB]
通讯作者: Scott,AB
Extraocular Muscle (EOM) Responses to Bupivacaine Injection
SELECTIVE REMOVAL OF EXTRAOCULAR MUSCLE
SELECTIVE REMOVAL OF EXTRAOCULAR MUSCLE
SELECTIVE REMOVAL OF EXTRAOCULAR MUSCLE
海外基金