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GENETIC MAPPING OF MOUSE CHROMOSOMAL GENES

GENETIC MAPPING OF MOUSE CHROMOSOMAL GENES
小鼠染色体基因的遗传图谱
批准号：
3809609
负责人：
C A KOZAK
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3809609
关键词：
DNA Retroviridae disease cell transformation chromosomes cytochromes electrophoresis gene expression genetic manipulation genetic mapping hybrid cells laboratory mouse murine leukemia virus nucleic acid hybridization nucleic acid sequence tissue /cell culture tumor antigens virus genetics

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中文摘要
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英文摘要
We have recently expanded our efforts to chromosomally map genes in the laboratory mouse. Such studies have received increased interest through the Human Genome Initiative, which views the mouse as a unique model system. Our studies, traditionally based on the analysis of somatic cell hybrids to assign genes to chromosomes, have been expanded to include Southern blot analysis of DNAs from an interspecies cross. These studies have resulted in the chromosomal mapping of genes encoding zona pellucida proteins and enzymes, genes involved in drug metabolism, brain-specific genes, and numerous genes involved in visual transduction, including a cDNA which may be responsible for retinal degeneration, an inherited disorder.
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GENETIC CONTROL OF RESISTANCE TO FRIEND VIRUS IN WILD MOUSE POPULATIONS
GENETIC ASPECTS OF VIRAL ONCOGENESIS IN MICES
GENETIC MAPPING OF MOUSE CHROMOSOMAL GENES
GENETIC ASPECTS OF VIRAL ONCOGENESIS IN WILD MOUSE SPECIES