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CELLULAR GENES INVOLVED IN TRANSFORMATION AND MULV TRANSMISSION IN INBRED MICE

CELLULAR GENES INVOLVED IN TRANSFORMATION AND MULV TRANSMISSION IN INBRED MICE
近交系小鼠中参与转化和多病毒传播的细胞基因
批准号：
3960532
负责人：
C A KOZAK
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3960532
关键词：
cytogenetics gene expression genetic mapping genetic recombination genetic regulation hybrid cells interferons mammary tumor virus molecular biology molecular cloning murine leukemia virus neoplasm /cancer genetics nucleic acid sequence oncogenes provirus structural genes tissue /cell culture viral leukemogenesis virus genetics

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中文摘要
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英文摘要
Genetic studies on the transmission of murine retroviruses through the mouse germline, susceptibility to exogenous infection, and virus-induced oncogenesis have led to the identification and chromosomal mapping of numerous genetic loci involved in these phenomena. These studies rely on the analysis of somatic cell hybrids either alone or in conjunction with classical Mendelian crosses. The genes under investigation include proviral integration sites for various mammary tumor viruses and MuLVs, the cellular homologs of several oncogenes, and tumor-associated integration sites. Hybrids have also been used to map several other genes for which cloned probes are available including interferon and Alpha-, Beta-spectrin.
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GENETIC CONTROL OF RESISTANCE TO FRIEND VIRUS IN WILD MOUSE POPULATIONS
GENETIC ASPECTS OF VIRAL ONCOGENESIS IN MICES
GENETIC MAPPING OF MOUSE CHROMOSOMAL GENES
GENETIC ASPECTS OF VIRAL ONCOGENESIS IN WILD MOUSE SPECIES
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