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ENDOTHELIUM-DERIVED NITRIC OXIDE AND EXERCISE INDUCED VASODILATION

ENDOTHELIUM-DERIVED NITRIC OXIDE AND EXERCISE INDUCED VASODILATION
内皮源性一氧化氮和运动引起的血管舒张
批准号：
3779640
负责人：
A A QUYYUMI
金额：
$0.0万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3779640
关键词：
exercise human subject nitric oxide vasodilatation vasodilators

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中文摘要
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英文摘要
The lining of blood vessels (endothelium) is capable of releasing a substance called endothelium-derived relaxant factor which causes relaxation of blood vessels. Continuous release of endothelium-derived relaxant factor maintains a low blood vessel tone. To investigate if the release of this factor is also important in causing relaxation of blood vessels that accompanies exercise of the muscle, we investigated the effect of a blocker of release of endothelium-derived relaxant factor in patients during forearm exercise. Up to 25% of the relaxation of blood vessels that occurs during exercise is due to release of endothelium- derived relaxant factor, suggesting an important role for this substance in the physiology of exercise.
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会议论文
EFFECTS OF ENDOTHELIUM-DERIVED RELAXANT FACTOR ON CORONARY RESISTANCE VESSELS
CIRCADIAN VARIATION IN ISCHEMIC THRESHOLD AND VASCULAR RESISTANCE IN CAD
EFFECT OF L-ARGININE ON ENDOTHELIUM-DEPENDENT CORONARY VASOMOTION
PLATELET INHIBITORY EFFECT OF ENDOTHELIUM-DERIVED RELAXING FACTOR
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