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PERIPHERAL VASCULAR ENDOTHELIAL DYSFUNCTION IN SYNDROME X

PERIPHERAL VASCULAR ENDOTHELIAL DYSFUNCTION IN SYNDROME X
X 综合征中的外周血管内皮功能障碍
批准号：
3779639
负责人：
A A QUYYUMI
金额：
$0.0万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3779639
关键词：
angina pectoris blood vessel disorder human subject nitric oxide peripheral nervous system disorders vascular endothelium vasodilators

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中文摘要
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英文摘要
We have previously demonstrated that certain patients with chest pain, despite having normal coronary arteries, have a malfunction of the lining of the blood vessels (endothelial dysfunction). To investigate if this abnormality in the lining of blood vessels is restricted to the heart or is a wide-spread phenomenon involving the peripheral circulation, we measured the capability of the endothelium to release endothelium-derived relaxant factor both in the heart and the leg vessels. There was a correlation between the responses in the two beds, suggesting that the dysfunction of the lining of blood vessels is generalized, and involves both vascular beds.
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