Defining the molecular and functional features of protective HIV-specific T cells

定义保护性 HIV 特异性 T 细胞的分子和功能特征

• 批准号: nhmrc : 1106756
• 负责人: A/Pr John Miles
• 金额: $ 40.59万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/defining-molecular-functional-t-cells/662933
• 关键词: Defining; molecular; functional; features; protective

Human immunodeficiency virus (HIV) directly attacks our immune system, impairing our natural defense against infection and disease. HIV has claimed over 39 million lives worldwide since its discovery, and no vaccine is currently available. Despite this, there are some individuals with a particular genetic advantage able to control HIV infection who never get sick. Understanding how these individuals control HIV so efficiently may lead to novel treatments or potential vaccines against HIV.

人类免疫缺陷病毒（HIV）直接攻击我们的免疫系统，损害我们对感染和疾病的自然防御。自发现以来，艾滋病毒已在全世界夺去了3900多万人的生命，目前还没有疫苗可用。尽管如此，仍有一些具有特殊遗传优势的人能够控制艾滋病毒感染，但他们永远不会生病。了解这些人如何如此有效地控制艾滋病毒可能会导致新的治疗方法或潜在的艾滋病毒疫苗。