Investigations into the biology and functionality of the human T cell receptor
Investigations into the biology and functionality of the human T cell receptor
批准号:
nhmrc : 613664
负责人:
A/Pr John Miles
金额:
$28.29万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2013-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
T lymphocytes play a pivotal role in the immune system by recognising virus-infected tissue and tumour cells through the use of specific cell surface receptors called T cell receptors (TCR). This project will study why partcular TCRs are used by the immune system, and will also examine the specificity of T cell recognition by determine the range of molecules an individual T cell can recognise. The work will aid in the development of new intelligent vaccines for cancer and infectious disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Using Methods in Genetic Epidemiology to Elucidate the Relationship Between Viral Infection and Risk of Autoimmune Disease
-
批准号:nhmrc : 1125141
-
项目类别:Project Grants
-
资助金额:$42.47万
-
财政年份:2017
-
负责人:A/Pr John Miles
-
依托单位:
Understanding and modulating the human immune system
-
批准号:nhmrc : GNT1131732
-
项目类别:Career Development Fellowships
-
资助金额:$47.01万
-
财政年份:2017
-
负责人:A/Pr John Miles
-
依托单位:
Using Methods in Genetic Epidemiology to Elucidate the Relationship Between Viral Infection and Risk of Autoimmune Disease
-
批准号:nhmrc : GNT1125141
-
项目类别:Project Grants
-
资助金额:$62.24万
-
财政年份:2017
-
负责人:A/Pr John Miles
-
依托单位:
Understanding and modulating the human immune system
-
批准号:nhmrc : 1131732
-
项目类别:Career Development Fellowships
-
资助金额:$32.12万
-
财政年份:2017
-
负责人:A/Pr John Miles
-
依托单位:
Defining the molecular and functional features of protective HIV-specific T cells
-
批准号:nhmrc : 1106756
-
项目类别:Project Grants
-
资助金额:$40.59万
-
财政年份:2016
-
负责人:A/Pr John Miles
-
依托单位:
Defining the molecular and functional features of protective HIV-specific T cells
-
批准号:nhmrc : GNT1106756
-
项目类别:Project Grants
-
资助金额:$59.2万
-
财政年份:2016
-
负责人:A/Pr John Miles
-
依托单位:
A new approach to the design and evaluation of T cell vaccines for cancer and infectious disease.
-
批准号:nhmrc : 1078987
-
项目类别:Project Grants
-
资助金额:$26.28万
-
财政年份:2015
-
负责人:A/Pr John Miles
-
依托单位:
Development of CD96 antibodies for cancer treatment
-
批准号:nhmrc : 1093566
-
项目类别:Development Grants
-
资助金额:$54.73万
-
财政年份:2015
-
负责人:A/Pr John Miles
-
依托单位:
Tracking the human immune system over years of life
-
批准号:nhmrc : GNT1069281
-
项目类别:Project Grants
-
资助金额:$45.64万
-
财政年份:2014
-
负责人:A/Pr John Miles
-
依托单位:
Determining the biological significance of allelic sequence variation within the T cell receptor loci
-
批准号:nhmrc : 1067374
-
项目类别:Project Grants
-
资助金额:$41.85万
-
财政年份:2014
-
负责人:A/Pr John Miles
-
依托单位:
Following the T cell repertoire over the human life course
-
批准号:nhmrc : 1069281
-
项目类别:Project Grants
-
资助金额:$31.55万
-
财政年份:2014
-
负责人:A/Pr John Miles
-
依托单位:
Tracking the impact of superinfection with a common Herpesvirus on T cell immunity in humans
-
批准号:nhmrc : 1045870
-
项目类别:Project Grants
-
资助金额:$21.19万
-
财政年份:2013
-
负责人:A/Pr John Miles
-
依托单位:
Investigations into supraphysiologic T cell receptors and T cell agonists.
-
批准号:nhmrc : 1031652
-
项目类别:Career Development Fellowships
-
资助金额:$27.23万
-
财政年份:2012
-
负责人:A/Pr John Miles
-
依托单位:
The role of long peptide epitopes in antiviral CD8+ T cell recognition.
-
批准号:nhmrc : 1021620
-
项目类别:Project Grants
-
资助金额:$28.98万
-
财政年份:2012
-
负责人:A/Pr John Miles
-
依托单位:
Investigations into the architectural and biophysical features of optimal T cell receptor design
-
批准号:nhmrc : 496721
-
项目类别:Early Career Fellowships
-
资助金额:$16.8万
-
财政年份:2008
-
负责人:A/Pr John Miles
-
依托单位:
Investigations into the cytolytic T cell response during Epstein-Barr virus related disease
-
批准号:nhmrc : 389937
-
项目类别:NHMRC Postgraduate Scholarships
-
资助金额:$0.25万
-
财政年份:2006
-
负责人:A/Pr John Miles
-
依托单位:
Cytotoxic T lymphocyte response to Epstein-Barr virus
-
批准号:nhmrc : 339480
-
项目类别:NHMRC Postgraduate Scholarships
-
资助金额:$2.81万
-
财政年份:2005
-
负责人:A/Pr John Miles
-
依托单位:
海外基金