Investigations into the architectural and biophysical features of optimal T cell receptor design
Investigations into the architectural and biophysical features of optimal T cell receptor design
批准号:
nhmrc : 496721
负责人:
A/Pr John Miles
金额:
$16.8万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2011-12-31
中文摘要
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英文摘要
Humans evolve slowly, pathogens and cancer evolve quickly. Unsurprisingly, our immune systems often lose this arms race and we irreversibly succumb to disease. Catastrophically, >26 million people are lost every year to the these causes. This project will use a new technology to rapidly advance the evolution of human immune receptors to construct a class of super-receptor. These super-receptors may prove decisive weapons in the fight against cancer and infectious disease.
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会议论文
Using Methods in Genetic Epidemiology to Elucidate the Relationship Between Viral Infection and Risk of Autoimmune Disease
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批准号:nhmrc : 1125141
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项目类别:Project Grants
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资助金额:$42.47万
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财政年份:2017
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负责人:A/Pr John Miles
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依托单位:
Understanding and modulating the human immune system
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批准号:nhmrc : GNT1131732
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项目类别:Career Development Fellowships
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资助金额:$47.01万
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财政年份:2017
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负责人:A/Pr John Miles
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依托单位:
Using Methods in Genetic Epidemiology to Elucidate the Relationship Between Viral Infection and Risk of Autoimmune Disease
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批准号:nhmrc : GNT1125141
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项目类别:Project Grants
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资助金额:$62.24万
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财政年份:2017
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负责人:A/Pr John Miles
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依托单位:
Understanding and modulating the human immune system
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批准号:nhmrc : 1131732
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项目类别:Career Development Fellowships
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资助金额:$32.12万
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财政年份:2017
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负责人:A/Pr John Miles
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依托单位:
Defining the molecular and functional features of protective HIV-specific T cells
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批准号:nhmrc : 1106756
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项目类别:Project Grants
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资助金额:$40.59万
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财政年份:2016
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负责人:A/Pr John Miles
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依托单位:
Defining the molecular and functional features of protective HIV-specific T cells
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批准号:nhmrc : GNT1106756
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项目类别:Project Grants
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资助金额:$59.2万
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财政年份:2016
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负责人:A/Pr John Miles
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依托单位:
A new approach to the design and evaluation of T cell vaccines for cancer and infectious disease.
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批准号:nhmrc : 1078987
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项目类别:Project Grants
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资助金额:$26.28万
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财政年份:2015
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负责人:A/Pr John Miles
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依托单位:
Development of CD96 antibodies for cancer treatment
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批准号:nhmrc : 1093566
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项目类别:Development Grants
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资助金额:$54.73万
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财政年份:2015
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负责人:A/Pr John Miles
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依托单位:
Tracking the human immune system over years of life
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批准号:nhmrc : GNT1069281
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项目类别:Project Grants
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资助金额:$45.64万
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财政年份:2014
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负责人:A/Pr John Miles
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依托单位:
Determining the biological significance of allelic sequence variation within the T cell receptor loci
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批准号:nhmrc : 1067374
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项目类别:Project Grants
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资助金额:$41.85万
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财政年份:2014
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负责人:A/Pr John Miles
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依托单位:
Following the T cell repertoire over the human life course
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批准号:nhmrc : 1069281
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项目类别:Project Grants
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资助金额:$31.55万
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财政年份:2014
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负责人:A/Pr John Miles
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依托单位:
Tracking the impact of superinfection with a common Herpesvirus on T cell immunity in humans
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批准号:nhmrc : 1045870
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项目类别:Project Grants
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资助金额:$21.19万
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财政年份:2013
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负责人:A/Pr John Miles
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依托单位:
Investigations into supraphysiologic T cell receptors and T cell agonists.
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批准号:nhmrc : 1031652
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项目类别:Career Development Fellowships
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资助金额:$27.23万
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财政年份:2012
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负责人:A/Pr John Miles
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依托单位:
The role of long peptide epitopes in antiviral CD8+ T cell recognition.
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批准号:nhmrc : 1021620
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项目类别:Project Grants
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资助金额:$28.98万
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财政年份:2012
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负责人:A/Pr John Miles
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依托单位:
Investigations into the biology and functionality of the human T cell receptor
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批准号:nhmrc : 613664
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项目类别:NHMRC Project Grants
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资助金额:$28.29万
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财政年份:2010
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负责人:A/Pr John Miles
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依托单位:
Investigations into the cytolytic T cell response during Epstein-Barr virus related disease
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批准号:nhmrc : 389937
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项目类别:NHMRC Postgraduate Scholarships
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资助金额:$0.25万
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财政年份:2006
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负责人:A/Pr John Miles
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依托单位:
Cytotoxic T lymphocyte response to Epstein-Barr virus
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批准号:nhmrc : 339480
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项目类别:NHMRC Postgraduate Scholarships
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资助金额:$2.81万
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财政年份:2005
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负责人:A/Pr John Miles
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依托单位:
海外基金