Following the T cell repertoire over the human life course

追踪人类生命历程中的 T 细胞库

• 批准号: nhmrc : 1069281
• 负责人: A/Pr John Miles
• 金额: $ 31.55万
• 依托单位: James Cook University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/following-t-cell-life-course/455384
• 关键词: Following; cell; repertoire; over; human

T cells are critical to human health being our second and last line against infectious disease and cancer. However, we know very little about how this important immune compartment operates on a top-down scale. This project will use new technology to resolve this immune compartment to high detail. We will then use this new method to track the T cell compartment from the first years of life and across years of adult life to see how this vital immune compartment evolves along the human life course.

T细胞对人类健康至关重要，是我们对抗传染病和癌症的第二道也是最后一道防线。然而，我们对这个重要的免疫区室如何自上而下地运作知之甚少。该项目将使用新技术来解决这个免疫区室的高度细节。然后，我们将使用这种新方法来跟踪生命最初几年和成年后几年的T细胞区室，以了解这种至关重要的免疫区室是如何沿着人类生命历程进化的。