NEUROBIOLOGY--CHILD DEVELOPMENT, AND DISEASE PATTERNS IN PRIMITIVE CULTURE

对正在消失的原始社会的人类生物学的研究集中在 不同文化背景下的神经发育和学习模式 在这种孤立的群体中发现的人类条件下的实验。 对人类孤立表达的问题的机会主义调查是 我们大多数研究的方法基础：库鲁-CJD，艾滋病毒 (艾滋病)、HTLV-I延缓中枢神经系统病毒感染、衰老和阿尔茨海默氏症 疾病、痴呆、肌萎缩侧索硬化症/帕金森病。分子遗传学、生物化学、 免疫学、病毒学和现场流行病学、临床、语言学和 文化隔离以及遗传和/或地理上的行为研究 孤立的基元波段产生的数据比 大都会社会。密克罗尼西亚探险队的数据和标本， 美拉尼西亚、波利尼西亚、南美洲、亚洲和非洲在 最近的HIV(AIDS)、HTLV-I、汉坦病毒、PML的JC病毒和疱疹病毒， 巨细胞病毒和EB病毒研究。关于营养、生殖、生育力、年龄的研究 青春期和衰老，遗传距离和多形性，不寻常和奇怪的用途 在语言学习、认知风格、 计算(没有文字或数字的计算)和文化修改 性行为阐明了神经功能的替代形式 一旦自然文化，我们就无法调查的人 在原始人类分离株上的实验被合并到 世界性的人类共同体。库鲁病、肌萎缩侧索硬化症/帕金森病、 L脊髓病，癫痫，家族性帕金森综合征，Viliuisk 脑病，其他中枢神经系统退行性疾病，歇斯底里障碍， 精神分裂症，肿瘤，甲状腺肿，克汀病，类风湿疾病， 糖尿病，哮喘，慢性肺部疾病，疟疾，丝虫病，麻风病， 囊虫病，以及这些孤立群体中的其他感染 意义重大的发现。由汉坦病毒引起的HFRS在亚洲、苏联、 对欧洲和美国新发现的汉坦病毒进行了研究。人类 对高海拔、潮湿或干旱气候的进化和适应，可变 食物供应、矿物质缺乏、有毒暴露和对严重的 对疾病或社会/心理压力进行适当的研究 人口。因此，HTLV-1和HIV逆转录病毒是中枢神经系统疾病的原因 在人类中首次发现是在孤立或社会隔离的群体中， 哥伦比亚图马科的TSP发病率焦点；纽约州纽瓦克的吸毒母亲 通常在这些与世隔绝或社会隔离的地方学习最好 组。

Studies of human biology of vanishing primitive societies focus on neurological development and learning patterns in diverse cultural experiments in the human condition found in such isolated groups. Opportunistic investigation of problems phrased by man in isolation is the basis of approach from which most of our studies evolved: kuru-CJD, HIV (AIDS), HTLV-I slow virus infections of the CNS, aging and Alzheimer's disease, dementia, ALS/PD. Techniques of molecular genetics, biochemistry, immunology, virology, and field epidemiological, clinical, linguistic and behavioral studies in cultural isolates and genetic and/or geographically isolated primitive bands yield more easily interpretable data than in cosmopolitan societies. Data and specimens from expeditions to Micronesia, Melanesia, Polynesia, South America, Asia and Africa provided valuable in recent HIV (AIDS), HTLV-I, Hantavirus, JC virus of PML and herpes virus, CMV and EBV studies. Studies on nutrition, reproduction, fertility, age of puberty and aging, genetic distance and pleomorphisms, unusual and odd use of the higher cortical functions in language learning, cognitive styles, computation (calculation without words or numbers) and culturally modified sexual behavior elucidate alternative forms of neurologic functioning for man which we would be unable to investigate once the natural cultural experiments in primitive human isolates are amalgamated into the cosmopolitan community of man. Foci of high incidence of kuru, ALS/PD, HTLV-L myelopathy, epilepsy, familial parkinsonism, Viliuisk encephalopathy, other CNS degenerations, hysterical disorders, schizophrenia, neoplasms, goiter, cretinism, rheumatoid diseases, diabetes, asthma, chronic lung disease, malaria, filariasis, leprosy, cysticercosis, and other infections in these isolated groups have yielded widely significant discoveries. HFRS caused by Hantaviruses in Asia, USSR, Europe and newly recognized Hantaviruses in the U.S. are studied. Human evolution and adaptability to high altitude, wet or arid climes, variable food supply, mineral deficiencies, toxic exposures and responses to severe diseases or social/psychological stress are studied in appropriate population. Thus, HTLV-1 and HIV retroviruses as causes of CNS diseases in man were first found in isolated or socially segregated groups, high incidence TSP focus in Tumaco, Colombia; drug using mothers in Newark, New Jersey and are often best studied in these isolated or socially segregated groups.