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NEUROBIOLOGY--CHILD DEVELOPMENT, AND DISEASE PATTERNS IN PRIMITIVE CULTURE

NEUROBIOLOGY--CHILD DEVELOPMENT, AND DISEASE PATTERNS IN PRIMITIVE CULTURE
神经生物学——原始文化中的儿童发育和疾病模式
批准号:
3922456
负责人:
D CARLETON GAJDUSEK
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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中文摘要
翻译
对正在消失的原始社会的人类生物学的研究集中在 不同文化背景下的神经发育和学习模式 在这种孤立的群体中发现的人类条件下的实验。 对人类孤立表达的问题的机会主义调查 是我们所有研究方法的基础。 分子生物学、免疫学、病毒学、 内分泌学和生物化学以及现场流行病学、临床、 文化隔离和遗传中的语言和行为研究 和/或地理上隔离的原始带更容易产生 可解释的数据比国际社会中的数据更容易理解。数据和 在密克罗尼西亚、波利尼西亚探险时收集的标本, 所罗门群岛、新赫布里底群岛、新几内亚、印度尼西亚、南部 使用的是美洲、亚洲和非洲。关于营养的研究, 生殖、生育、神经内分泌对性年龄的影响 成熟和衰老,遗传多态,遗传距离, 脑高级功能的异常和奇特用法 语言学习、认知方式、计算(使用- 文字或数字)和文化改变的性行为 阐明人类神经功能的替代形式 我们将无法调查一旦自然文化 在原始人类分离株上的实验被合并到 世界性的人类共同体。库鲁病高发地区, 肌萎缩侧索硬化症/帕金森病、癫痫、痉挛性瘫痪、家族性帕金森综合征等 中枢神经系统退行性变,歇斯底里障碍,精神分裂症,肿瘤, 甲状腺肿、克汀病、类风湿疾病、糖尿病、哮喘、慢性 肺部疾病、疟疾、丝虫病、麻风病、囊虫病和 其他感染也会被调查。出血性等人畜共患病 中国、日本、韩国、苏联、 斯堪的纳维亚半岛和巴尔干半岛被研究,包括这些新的 美国公认的本雅维拉病毒获得性免疫 本课题组在1950-1960年间研究的虚证 重新启动。人类进化和对高海拔的适应, 过度潮湿或干旱的气候、多变的食物供应、矿物质 缺乏、接触有毒物质和对严重疾病或 正在对社会/心理压力进行适当的调查 种群隔离。
英文摘要
Studies of human biology of vanishing primitive societies focus on neurological development and learning patterns in diverse cultural experiments in the human condition found in such isolated groups. Opportunistic investigation of problems phrased by man in isolation is the basis of approach from which all our studies have evolved. Techniques of molecular biology, immunology, virology, endocrinology and biochemistry and field epidemiological, clinical, linguistic and behavioral studies in cultural isolates and genetic and/or geographically isolated primitive bands yield more easily interpretable data than in cosmopolitan societies. Data and specimens collected on expeditions to Micronesia, Polynesia, Solomon Islands, New Hebrides, New Guinea, Indonesia, South America, Asia and Africa are used. Studies on nutrition, reproduction, fertility, neuroendocrine influences on age of sexual maturation and aging, genetic polymorphisms, genetic distance, unusual and odd employment of the higher cerebral functions in language learning, cognitive styles, computation (calculation with- out words or numbers) and culturally modified sexual behavior elucidate alternative forms of neurologic functioning for man which we would be unable to investigate once the natural cultural experiments in primitive human isolates are amalgamated into the cosmopolitan community of man. Foci of high incidence of kuru, ALS/PD, epilepsy, spastic paraparesis, familial parkinsonism, other CNS degenerations, hysterical disorders, schizophrenia, neoplasms, goiter, cretinism, rheumatoid diseases, diabetes, asthma, chronic lung disease, malaria, filariasis, leprosy, cysticercosis, and other infections are investigated. Zoonoses such as hemorrhagic fever with renal syndrome in China, Japan, Korea, USSR, Scandinavia, and the Balkans are studied including these newly recognized Bunyawera viruses in the U.S. Acquired immune deficiency syndrome studied by our group in 1950-1960 have been reinitiated. Human evolution and adaptability to high altitude, excessively wet or arid climes, variable food supply, mineral deficiencies, toxic exposures and responses to severe diseases or social/psychological stress are under investigation in appropriate population isolates.
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CHRONIC CNS DISEASE STUDIES--SLOW, LATENT AND TEMPERATE VIRUS INFECTION
CHRONIC CNS DISEASE STUDIES--SLOW, LATENT AND TEMPERATE VIRUS INFECTIONS
NEUROBIOLOGY--CHILD DEVELOPMENT, AND DISEASE PATTERNS IN PRIMITIVE CULTURE
CHRONIC CNS DISEASE STUDIES--SLOW, LATENT AND TEMPERATE VIRUS INFECTION
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