TRIAL OF ISONIAZID FOR ACTION TREMOR

异烟肼治疗动作性震颤的试验

• 批准号: 3922573
• 负责人: M HALLETT
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3922573
• 关键词: cerebellar disorders; human subject; human therapy evaluation; isoniazid; multiple sclerosis; neuromuscular disorder chemotherapy; tremor

Previous studies have shown utility of isoniazid for ameliorating cerebellar postural tremor in patients with multiple sclerosis. Current studies are aimed at identifying whether patients with action tremors of other types are also benefitted. A double-blind placebo-controlled, cross-over trial is in progress. Twenty patients have now been studied. Isoniazid does appear to help some of these cases, but we do not have enough experience yet to predict the response.

先前的研究已表明异烟肼可用于改善 多发性硬化患者小脑姿势性震颤 目前的研究旨在确定是否有 其他类型的动作震颤也是有益的。 一项双盲 安慰剂对照交叉试验正在进行中。 二十 病人已经被研究过了。 异烟肼似乎确实有助于一些 但我们还没有足够的经验来预测 的反应。