PHYSIOLOGICAL ANALYSIS OF VOLUNTARY MOVEMENT

随意运动的生理分析

• 批准号: 4696969
• 负责人: M HALLETT
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4696969
• 关键词: brain disorders; electromyography; evoked potentials; hemiplegia; human subject; proprioception /kinesthesia; stretch reflex; stroke

A laboratory is being set up for analysis of balance. This will enable simultaneous study of body angles, foot-floor forces and multiple EMGs. We hope to identify normal mechanisms of balance and how these are deranged in patients. The study of motor control in hemiplegia is being set up as the major project of the Unit. Patients with discrete brain lesions will be studied; patients with strokes will be the main group, and many patients will be followed serially from onset of the disorder to recovery. We hope to discover pathophysiological mechanisms including those mechanisms underlying recovery. Methods of study will include (1) quantitative clinical battery, (2) evoked potentials, (3) pre-motor potentials, (4) stretch reflexes, (5) EMG analysis of voluntary movements, and (6) PET scanning during voluntary movement.

正在建立一个分析平衡的实验室。 这将使 同时研究身体角度，足底力和多种肌电图。 我们 我希望能找出正常的平衡机制，以及这些机制是如何被扰乱的， 患者 偏瘫运动控制的研究正在被设立为专业 单位的项目。 将研究离散性脑病变患者; 中风患者将是主要群体，许多患者将 从疾病发作到康复进行连续跟踪。 我们希望 发现病理生理机制，包括那些机制 基本恢复。 研究方法将包括（1）定量 临床成套检查，（2）诱发电位，（3）运动前电位，（4） 牵张反射，（5）自主运动的EMG分析，和（6）PET 在随意运动时进行扫描。