STUDY OF HEPATITIS B VIRUS SURFACE ANTIGEN POLYPEPTIDE COMPONENTS IN SERA

血清中乙型肝炎病毒表面抗原多肽成分的研究

• 批准号: 4691951
• 负责人: J W SHIH
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4691951
• 关键词: antibody specificity; hepatitis B antigens; hepatitis B virus group; human subject; immunologic assay /test; pathologic process; serology /serodiagnosis; surface antigens

Procedures are being developed to examine polypeptide components of HBsAg from small quantities of patients' sera without prior extensive purification. The number and quantity of the polypeptides of each sample are studied after Western blot exposure to a panel of standard antibodies. This procedure allows one to examine serial serum samples from a patient during the course of disease and to identify the relatedness of the virus in cases with multiple exposure.

目前正在开发检测HBsAg多肽成分的程序 从少量的患者血清中， 洁净. 每份样品的多肽数量和含量 在Western印迹暴露于一组标准抗体后进行研究。 该程序允许检查来自患者的系列血清样品 并确定病毒的相关性 在多次接触的情况下。