Publishing Protein Databases on the Web Using dbEngine

有必要以一种可以立即访问互联网的科学界的方式轻松地发布数据。我们开发了一个简单的数据库搜索引擎dbEngine，它被用来在万维网（WWW）服务器上快速创建一个可搜索的数据库。数据可以从电子表格程序（Excel等）或从关系数据库系统导出的表中准备。这个通用网关接口（CGI-BIN）程序与WWW服务器一起使用，例如商业上可用的，或来自NCSA或CERN的。其功能包括：1)通过与and或or相关的词的组合搜索记录；2)将搜索结果作为超文本链接返回到其他WWW数据库服务器；3)将文献标识符列表映射到完整的参考文献；4)在图片和数据库之间建立双向超文本链接。DbEngine是为MitoDat数据库（与线粒体相关的孟德尔和非孟德尔遗传）Lemkin P. F., et al., Electrophoresis 17(2): 556- 72,1996 （http://www-lecb.ncifcrf.gov/mitoDat/）开发的。我们建立了一个磷蛋白数据库（http://www-lecb.ncifcrf.gov/phosphoDB/）以及其他几个蛋白质数据库。蛋白质的位置可以通过二维凝胶电泳图可视化。交互式2D地图还允许用户通过点击蛋白质直接访问特定的数据库条目。我们还在互联网数据库（http://www-lecb.ncifcrf.gov/2dwgDB/）中找到的2D凝胶图像的2DWG元数据库中使用dbEngine。这些数据库整合了来自各种生物数据库的信息，如GenBank、Swiss-Prot、GDB、OMOM等。我们的合作者定期更新数据库。Z01 BC 10043-04

There is a need to easily publish data in a way that is immediately accessible to the scientific community who have access to the Internet. We have developed a simple database search engine dbEngine which is being used to quickly create a searchable database on World Wide Web (WWW) servers. Data can be prepared from spreadsheet programs (Excel, etc.) or from tables exported from relational database systems. This Common Gateway Interface (CGI-BIN) program is used with a WWW server such as available commercially, or from NCSA or CERN. Its capabilities include: 1) searching records by combinations of terms connected with ANDs or ORs; 2) returning search results as hypertext links to other WWW database servers; 3) mapping lists of literature reference identifiers to the full references; and 4) creating bidirectional hypertext links between pictures and the database. DbEngine was developed for the MitoDat database (Mendelian and non-Mendelian Inheritance associated with the Mitochondrion) Lemkin P. F., et al., Electrophoresis 17(2): 556-72, 1996 (http://www-lecb.ncifcrf.gov/mitoDat/). We had established a phosphoprotein database (http://www-lecb.ncifcrf.gov/phosphoDB/) as well as several other protein databases. The locations of proteins may be visualized by 2D gel electrophoresis maps. Interactive 2D maps also let the user access specific database entries directly by clicking on proteins. We also use dbEngine in our 2DWG meta-database of 2D gel images found in Internet databases (http://www-lecb.ncifcrf.gov/2dwgDB/). These databases consolidate information from the various biological databases, e.g., GenBank, Swiss-Prot, GDB, OMOM, etc. Our collaborators periodically update the database. Z01 BC 10043-04