Infrastructure for Stem Cell Production & Distribution

干细胞生产基础设施

• 批准号: 6619338
• 负责人: JOSEPH ITSKOVITZ-ELDOR
• 金额: $ 40万
• 依托单位: TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2005-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6619338
• 关键词: Internet; SCID mouse; cell bank /registry; cell differentiation; clinical research; human embryonic stem cell line; karyotype; laboratory mouse; method development; surface antigens; teratoma; tissue /cell preparation; training; transcription factor

DESCRIPTION (provided by applicant): The aim of this application is to make the lines of human ES cells listed on the NIH Human ES cells registry available to the research community worldwide. We aim to be able to distribute 200 aliquots of human ES cells (each containing at least 2x10(6) cell) during the first year, and to double the production and distribution rate during the second year. We will also provide training to recipients which will include: lab manual, hands-on training and a web site support. To ensure the scale-up of high quality human ES cells under tight quality control processes (Good Laboratory Practice), we wish to establish a new fully-equipped laboratory and increase the number of the well-trained biologists. The team will also be involved in basic research aiming at improving human ES-cells. And to explore the variation in growth requirements and differentiation capacity of human ES cell lines. This will significantly increase the potential of research applications of human ES cells and the rate of discoveries of potential human ES cell-derived therapies for treating some of the most common and devastating human diseases.

描述（由申请人提供）：本申请的目的是使NIH人类胚胎干细胞注册表上列出的人类胚胎干细胞系可供全球研究界使用。