MESA FAMILY STUDY

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究将检验记忆训练技术在被归类为轻度认知障碍(MCI)的健康老年人(例如，Jennings&Jacoby，出版社)中被证明非常成功的有效性。MCI患者将被筛选，排除那些可能阻碍记忆力增强的疾病，如甲状腺问题，然后50名健康的MCI参与者将接受为期2周的回忆训练(训练组)或使用自我指导材料(控制组)。将在基线、训练后1周和6个月后评估记忆和认知功能，以评估训练组相对于对照组的成功程度、任何训练效果的概括和成果的维持。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will examine the effectiveness of a Recollection Training technique that has proven highly successful in healthy older adults (e.g., Jennings & Jacoby, in press) with individuals classified as having Mild Cognitive Impairment (MCI). MCI individuals will be screened to exclude those with conditions that may prevent memory enhancement, such as thyroid problems, and 50 healthy MCI participants will then receive either 2 weeks of Recollection Training (training group) or will work with self-instructional materials (control group). Memory and cognitive functioning will be assessed at baseline, 1 week after training, and 6 months later to assess the success of the training group relative to the control group, generalization of any training effects, and maintenance of gains.