MESA FAMILY STUDY

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。这项研究将检验回忆训练技术的有效性，该技术已被证明在健康的老年人（如詹宁斯和雅各比，出版）中非常成功，这些老年人被归类为轻度认知障碍（MCI）。MCI个体将被筛选以排除那些可能阻碍记忆增强的条件，如甲状腺问题，然后50名健康的MCI参与者将接受两周的回忆训练（训练组）或自学材料（对照组）。记忆和认知功能将在基线、训练后1周和6个月后进行评估，以评估训练组相对于对照组的成功程度、任何训练效果的普遍化以及收益的维持情况。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will examine the effectiveness of a Recollection Training technique that has proven highly successful in healthy older adults (e.g., Jennings & Jacoby, in press) with individuals classified as having Mild Cognitive Impairment (MCI). MCI individuals will be screened to exclude those with conditions that may prevent memory enhancement, such as thyroid problems, and 50 healthy MCI participants will then receive either 2 weeks of Recollection Training (training group) or will work with self-instructional materials (control group). Memory and cognitive functioning will be assessed at baseline, 1 week after training, and 6 months later to assess the success of the training group relative to the control group, generalization of any training effects, and maintenance of gains.