Training Program in Brain Tumor Biology

描述（由申请人提供）：UAB脑肿瘤生物学综合培训计划的申请提供了该领域独立研究科学家发展所需的严格的跨学科教育。该培训计划是基于细胞生物学，病理学和外科部门。培训计划的16名教师是根据他们在基础和转化脑肿瘤研究，动态研究计划和培训记录方面的互补研究专业知识选择的。研究项目包括：研究脑肿瘤迁移/侵袭、血管生成、细胞表面受体启动的信号传导、细胞凋亡的调节和新的病毒治疗方法的分子方面。学员接触到这种疾病的全方位知识和实验方法将通过脑肿瘤生物学的新研究生课程，每周脑肿瘤研究会议，每月脑肿瘤研究和治疗研讨会系列以及年度UAB脑肿瘤生物学科学务虚会正式整合。 培训计划将由Etty Benveniste博士（主任）、Candece Gladson博士 （联合主任）和Jim Markert博士（联合主任）以及执行委员会（Benos、吉莱斯皮、Roth和Sontheimer博士）。这组教员将负责制定个人培训计划，整合研究和教学内容，监督正式要求，招聘，正式申请的竞争性审查，以及监督受训人员的进展。该培训计划的另一个优势是与UAB脑肿瘤孢子补助金（PI：Yancey吉莱斯皮博士）和UAB综合癌症中心神经肿瘤学计划的密切联系。申请资助的对象包括博士前高级研究生和博士后受训人员。因此，在脑肿瘤生物学培训计划将准备未来的研究人员在这个重要的和临床相关的研究领域。

DESCRIPTION (provided by applicant): This application for a comprehensive Training Program in Brain Tumor Biology at UAB offers the rigorous interdisciplinary education required for the development of independent research scientists in this field. The Training Program is based in the Departments of Cell Biology, Pathology, and Surgery. The 16 faculty members of the Training Program have been selected based on their complementary research expertise in basic and translational brain tumor research, dynamic research programs, and training records. Research projects include: studies of the molecular aspects of brain tumor migration/invasion, angiogenesis, cell surface receptor-initiated signaling, the regulation of apoptosis, and novel viral approaches to therapy. The exposure of the trainees to the full spectrum of intellectual and experimental approaches to this disease will be integrated formally through a new graduate level course in Brain Tumor Biology, a weekly Brain Tumor Research Conference, a monthly Brain Tumor Research and Treatment Seminar Series, and an annual UAB Brain Tumor Biology Scientific Retreat. The Training Program will be administered by Dr. Etty Benveniste (Director), Dr. Candece Gladson (Co-Director), and Dr. Jim Markert (Co-Director), and by an Executive Committee (Drs. Benos, Gillespie, Roth and Sontheimer). This group of faculty will be responsible for development of individual training plans, integration of research and didactic components, oversight of formal requirements, recruitment, competitive review of formal applications, and oversight of the trainees' progress. An additional strength of this Training Program is the close association with the UAB Brain Tumor SPORE Grant (PI: Dr. Yancey Gillespie), and the UAB Comprehensive Cancer Center Neuro-Oncology Program. Funding is requested for both advanced pre-doctoral students and postdoctoral trainees. Thus, this Training Program in Brain Tumor Biology will prepare future investigators in this important and clinically relevant area of research.