Training Program in Brain Tumor Biology

描述（由申请人提供）：此申请为UAB脑肿瘤生物学综合培训计划提供严格的跨学科教育，以培养该领域的独立研究科学家。该培训计划以细胞生物学、病理学和外科部门为基础。培训计划的16名教师是根据他们在基础和转化脑肿瘤研究、动态研究项目和培训记录方面的互补研究专长而选择的。研究项目包括：脑肿瘤迁移/侵袭的分子研究，血管生成，细胞表面受体启动信号，细胞凋亡的调控，以及新的病毒治疗方法。通过新的脑肿瘤生物学研究生课程，每周一次的脑肿瘤研究会议，每月一次的脑肿瘤研究和治疗系列研讨会，以及每年一次的UAB脑肿瘤生物学科学静修，学员们将全面接触到这种疾病的智力和实验方法。

DESCRIPTION (provided by applicant): This application for a comprehensive Training Program in Brain Tumor Biology at UAB offers the rigorous interdisciplinary education required for the development of independent research scientists in this field. The Training Program is based in the Departments of Cell Biology, Pathology, and Surgery. The 16 faculty members of the Training Program have been selected based on their complementary research expertise in basic and translational brain tumor research, dynamic research programs, and training records. Research projects include: studies of the molecular aspects of brain tumor migration/invasion, angiogenesis, cell surface receptor-initiated signaling, the regulation of apoptosis, and novel viral approaches to therapy. The exposure of the trainees to the full spectrum of intellectual and experimental approaches to this disease will be integrated formally through a new graduate level course in Brain Tumor Biology, a weekly Brain Tumor Research Conference, a monthly Brain Tumor Research and Treatment Seminar Series, and an annual UAB Brain Tumor Biology Scientific Retreat. The Training Program will be administered by Dr. Etty Benveniste (Director), Dr. Candece Gladson (Co-Director), and Dr. Jim Markert (Co-Director), and by an Executive Committee (Drs. Benos, Gillespie, Roth and Sontheimer). This group of faculty will be responsible for development of individual training plans, integration of research and didactic components, oversight of formal requirements, recruitment, competitive review of formal applications, and oversight of the trainees' progress. An additional strength of this Training Program is the close association with the UAB Brain Tumor SPORE Grant (PI: Dr. Yancey Gillespie), and the UAB Comprehensive Cancer Center Neuro-Oncology Program. Funding is requested for both advanced pre-doctoral students and postdoctoral trainees. Thus, this Training Program in Brain Tumor Biology will prepare future investigators in this important and clinically relevant area of research.