Interdisciplinary Training: Neurodevelopmental Toxicology(RMI)

描述（由申请人提供）：本申请申请在哈佛大学公共卫生学院建立神经发育毒理学博士后跨学科培训项目。该计划将以环境卫生部门的暴露、流行病学和风险计划为基础。培训计划的结构遵循一个概念模型，强调要深入理解接触有毒物质和神经发育之间的联系，就需要解释宿主和环境因素可能改变这种联系的方式。本计划考虑的这些修饰因素的主要类别是：共同暴露于其他神经毒物，基因型，营养状况和社会环境。因此，将为受训者提供五个培训方向：暴露评估/环境健康、神经发育、遗传学、营养和社会环境。鉴于该方案的重点，所有受训者将有望发展暴露评估/环境健康、神经发育和流行病学/生物统计学（特别是适用于多层次数据集的分析方法）方面的专门知识。对于每个轨道，我们指定了一套核心能力，必修课程，临床经验的机会（如果相关），和研讨会系列。作为博士培训的一部分，即将到来的受训者将在一个或多个项目学科中发展专业知识。因此，该计划的目标将是提供一个或多个额外领域的交叉培训，以便在获得跨学科专业知识后，学员可以进行神经发育毒理学研究，更直接地满足风险评估人员的需求。这个为期三年的项目每年将招收两名新学员。代表该项目所有学科的34名教员已被招募为实习导师。学院成员目前进行了大量的多学科研究，这将为学员提供将他们的培训应用于正在进行的研究项目的现成机会。

DESCRIPTION (provided by applicant): This application requests funds to establish a post-doctoral Interdisciplinary Training Program in Neurodevelopmental Toxicology at the Harvard School of Public Health. The Program will be based in the Exposure, Epidemiology, and Risk Program of the Dept. of Environmental Health. The structure of the training program follows from a conceptual model emphasizing that a deep understanding of the association between exposure to a toxicant and neurodevelopment requires explication of the ways in which host and environmental factors might modify the association. The major categories of such modifying factors considered in this Program are: co-exposures to other neurotoxicants, genotype, nutritional status, and the social environment. Therefore, five Training Tracks will be offered to trainees: Exposure Assessment/Environmental Health, Neurodevelopment, Genetics, Nutrition, and Social Environment. Given the focus of the Program, all trainees will be expected to develop expertise in exposure assessment/environmental health, neurodevelopment, and epidemiology/biostatistics (particularly the analytic methods appropriate for multi-level data sets). For each track, we specify a set of core competencies, required course work, opportunities for clinical experiences (if relevant), and seminar series. Incoming trainees will have developed expertise in one of more of the Program disciplines as part of their doctoral training. The goal of the Program, therefore, will be to provide cross-training in one or more additional areas so that, having acquired interdisciplinary expertise, the trainee can conduct neurodevelopmental toxicology studies that more directly address the needs of risk assessors. Each year, two new trainees will be accepted into the three-year program. A 34-member faculty, representing all disciplines included in the Program, has been recruited to serve as trainee mentors. Members of the faculty currently conduct a wealth of multidisciplinary research, which will provide trainees with ready opportunities to apply their training in ongoing research projects.