CLINICAL DIAGNOSIS/BEHAVIORAL ASSESSMENT CORE

临床诊断/行为评估核心

• 批准号: 8076867
• 负责人: Harold Hill Goldsmith
• 金额: $ 14.35万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8076867
• 关键词: Address; Adolescence; Adolescent; Affect; Age; Anxiety; Anxiety Disorders; Behavior; Behavior assessment; Behavioral; Child; Code; DSM-IV; Data; Development; Diagnosis; Diagnostic; Ensure; Health behavior; Interview; Laboratories; Licensing; Literature; Longitudinal Studies; Measures; Mood Disorders; Paper; Participant; Problem behavior; Protocols documentation; Psychometrics; Psychopathology; Publishing; Questionnaires; Receiver Operating Characteristics; Risk Factors; Sampling; Scheme; Screening procedure; Structure; Symptoms; Trier Social Stress Test; Videotape; Visit; clinical Diagnosis; human subject; innovation; instrument

The Clinical Diagnosis/Behavioral Assessment Core (Core C) will be responsible for ensuring that a common set of age appropriate, interview, behavioral, and diagnostic measures are used in all projects that employ human subjects. The aims of Projects 2 and 3 are highly complementary; thus, they employ similar protocols for the laboratory visits done in the late adolescent age period. As a central activity, the core will conduct structured diagnostic interviews by licensed clinicians on select groups of participants, thus following up on diagnoses made earlier in these longitudinal studies and benefiting Projects 2, 3, 4, and 5. These K-SADS interviews will allow results to be assimilated to the literature on anxiety disorders as defined by DSM-IV. The presence or absence of clinical diagnoses will prominently figure into addressing scientific aims on Projects 2, 3, 4, and 5. Core C will pay for diagnostic interviews and manage the resulting data. Projects 2 and 3 will screen their entire samples for behavioral problems in late adolescence, with the MacArthur Health and Behavior Questionnaire (HBQ) as the main screening instrument. The projects will conduct this screening, but Core C will manage the resulting data in a uniform manner and facilitate analyses across projects. The Trier Social Stress Test (TSST) figures prominently in both Project 2 and 3, and relates conceptually to all projects. Core 2 will facilitate uniform administration of the TSST and conduct behavioral coding of videotapes taken during the TSST. The development and implementation of a coding scheme for affect and behavior during the TSST will be an innovative contribution of Core C. Finally, with our consultant Dr. Kraemer on Project 2, the Core will publish methodological papers on two topics: (1) Clarifying the relationship between categorical field diagnoses of child psychopathology and prior and concurrent dimensional symptom scores from the HBQ and other measures using Receiver Operating Characteristic (ROC) curve approaches. Many developmental factors will be incorporated into these analyses. (2) Examining the psychometric quality of instruments used in the assessment protocols. These latter measures capture key risk factors for adolescent anxiety.

临床诊断/行为评估核心(核心C)将负责确保 在所有雇用员工的项目中使用一套适合年龄的、访谈、行为和诊断措施 人类受试者。项目2和项目3的目标具有很强的互补性；因此，它们采用了相似的协议 对于在青春期后期进行的实验室访问。 作为一项中心活动，中心将由有执照的临床医生进行有组织的诊断访谈 参与者小组，从而跟踪这些纵向研究中早些时候做出的诊断 受益项目2、3、4和5。这些K-SADS访谈将使结果被吸收到 关于DSM-IV定义的焦虑症的文献。临床诊断的存在或缺失将 突出考虑解决项目2、3、4和5的科学目标。核心C将为诊断买单 访谈和管理由此产生的数据。 项目2和项目3将对其整个样本进行青春期晚期的行为问题筛查， 以麦克阿瑟健康与行为问卷(HBQ)为主要筛查工具。这些项目将 执行此筛选，但核心C将以统一的方式管理结果数据并促进分析 跨项目。 Trier社会压力测试(TSST)在项目2和项目3中都占有重要地位，并在概念上相关 所有的项目。CORE 2将促进TSST的统一管理，并进行行为编码 TSST期间拍摄的录像带。一种用于EFECT和AND编码方案的开发与实现 TSST期间的行为将是Core C的创新贡献。 最后，与我们的顾问Kraemer博士一起参与项目2，核心将发表关于两个项目的方法学论文 主题：(1)澄清儿童精神病理学的范畴现场诊断与先前的关系 以及来自HBQ和使用接收器操作的其他测量的并发维度症状分数 特征(ROC)曲线接近。许多发展因素将被纳入其中 分析。(2)检查评估方案中使用的工具的心理测量质量。这些 后一种措施捕捉到了青少年焦虑的关键风险因素。