CLINICAL DIAGNOSIS/BEHAVIORAL ASSESSMENT CORE

临床诊断/行为评估核心

• 批准号: 8076867
• 负责人: Harold Hill Goldsmith
• 金额: $ 14.35万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8076867
• 关键词: Address; Adolescence; Adolescent; Affect; Age; Anxiety; Anxiety Disorders; Behavior; Behavior assessment; Behavioral; Child; Code; DSM-IV; Data; Development; Diagnosis; Diagnostic; Ensure; Health behavior; Interview; Laboratories; Licensing; Literature; Longitudinal Studies; Measures; Mood Disorders; Paper; Participant; Problem behavior; Protocols documentation; Psychometrics; Psychopathology; Publishing; Questionnaires; Receiver Operating Characteristics; Risk Factors; Sampling; Scheme; Screening procedure; Structure; Symptoms; Trier Social Stress Test; Videotape; Visit; clinical Diagnosis; human subject; innovation; instrument

The Clinical Diagnosis/Behavioral Assessment Core (Core C) will be responsible for ensuring that a common set of age appropriate, interview, behavioral, and diagnostic measures are used in all projects that employ human subjects. The aims of Projects 2 and 3 are highly complementary; thus, they employ similar protocols for the laboratory visits done in the late adolescent age period. As a central activity, the core will conduct structured diagnostic interviews by licensed clinicians on select groups of participants, thus following up on diagnoses made earlier in these longitudinal studies and benefiting Projects 2, 3, 4, and 5. These K-SADS interviews will allow results to be assimilated to the literature on anxiety disorders as defined by DSM-IV. The presence or absence of clinical diagnoses will prominently figure into addressing scientific aims on Projects 2, 3, 4, and 5. Core C will pay for diagnostic interviews and manage the resulting data. Projects 2 and 3 will screen their entire samples for behavioral problems in late adolescence, with the MacArthur Health and Behavior Questionnaire (HBQ) as the main screening instrument. The projects will conduct this screening, but Core C will manage the resulting data in a uniform manner and facilitate analyses across projects. The Trier Social Stress Test (TSST) figures prominently in both Project 2 and 3, and relates conceptually to all projects. Core 2 will facilitate uniform administration of the TSST and conduct behavioral coding of videotapes taken during the TSST. The development and implementation of a coding scheme for affect and behavior during the TSST will be an innovative contribution of Core C. Finally, with our consultant Dr. Kraemer on Project 2, the Core will publish methodological papers on two topics: (1) Clarifying the relationship between categorical field diagnoses of child psychopathology and prior and concurrent dimensional symptom scores from the HBQ and other measures using Receiver Operating Characteristic (ROC) curve approaches. Many developmental factors will be incorporated into these analyses. (2) Examining the psychometric quality of instruments used in the assessment protocols. These latter measures capture key risk factors for adolescent anxiety.

临床诊断/行为评估核心（核心C）将负责确保共同 所有采用的项目都使用适合年龄，访谈，行为和诊断措施 人类主题。项目2和3的目的是高度互补的。因此，他们采用类似的协议 对于青少年晚期的实验室访问。 作为一项中心活动，核心将对有执照的临床医生进行结构化的诊断访谈 一组参与者，因此跟进这些纵向研究中早些时候进行的诊断和 受益于项目2、3、4和5。这些K-SADS访谈将允许结果吸收到 DSM-IV定义的有关焦虑症的文献。临床诊断的存在或不存在 明显地解决科学目标对项目2、3、4和5的目标。CoreC将为诊断付费 采访并管理结果数据。 项目2和3将在青春期后期筛选其全部样本，以解决行为问题， 麦克阿瑟健康与行为问卷（HBQ）作为主要筛选工具。项目将 进行此筛选，但是Core C将以统一的方式管理产生的数据并促进分析 跨项目。 在项目2和3中，Trier社会压力测试（TSST）都显着，并在概念上关联 所有项目。 Core 2将促进TSST的统一给药并进行行为编码 在TSST期间拍摄的录像带。为影响和 TSST期间的行为将是CoreC的创新贡献。 最后，与我们的顾问Kraemer博士在项目2上，核心将在两篇文章上发表方法论论文 主题：（1）澄清儿童心理病理学的分类现场诊断与先验的关系之间的关系 以及使用接收器运行的HBQ和其他措施的同时尺寸症状得分 特征（ROC）曲线方法。许多发展因素将纳入这些因素 分析。 （2）检查评估方案中使用的工具的心理测量质量。这些 后者的措施捕获了青少年焦虑的关键危险因素。