Neuroscience Advanced Predoctoral Institutional Training Grant

神经科学高级博士前机构培训补助金

• 批准号: 8066606
• 负责人: JEROME N SANES
• 金额: $ 17.76万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8066606
• 关键词: Grant; Neurosciences; Training; pre-doctoral

DESCRIPTION (provided by applicant): The central objective of this pre-doctoral training program in Neuroscience is to continue providing individualized, high quality training to pre-doctoral students in their middle-to-late years of graduate studies as they prepare to finish their dissertation research. We provide broad, multi-disciplinary training at all levels with a strong foundation in core concepts, skills, methodologies, and advanced comprehension of the scientific literature. Our newly revised core curriculum instructs students at the level of genes, cells, systems, cognition, translational neuroscience, and diseases of the nervous system. We foster an environment unconstrained by traditional discipline boundaries and where graduate students are encouraged to work at the interfaces of these disciplines. At all stages of instruction, we integrate skills considered essential for successful, independent research careers in neuroscience. These include critical thinking and reasoning, effective science writing and oral presentation, knowledge of scientific review processes, and training in ethics. For this program, we will expand recent initiatives to ensure that graduate students have exposure to clinical and disease concepts in neuroscience. These include incorporating seminars from clinicians at Brown into our core curriculum, attendance at Grand Rounds in Neurology, Neuropathology, and Psychiatry at Brown-affiliated Hospital; and compulsory attendance in Year 3 of a new graduate-student only Neurobiology of Disease Course. The majority of our pre-doctoral trainees continue in basic scientific investigations of the nervous system either in academia or in the biotechnology industry. We expect that exposure to clinical issues early in their training will positively influence their research careers. Key features of the Neuroscience Graduate Program at Brown include: Excellence in research along with excellence in education and mentorship; a history of interdisciplinary and translational research particularly in computational neuroscience; and an environment of small but highly productive laboratories where graduate students are equal partners in the research process. The proposed training program has 29 participating faculty, drawn from six different Brown University departments and a target of about 50 pre-doctoral trainees. The faculty trainers are a distinguished and energetic group of brain scientists that collectively cover the spectrum of modern neuroscience research from genes to cognition. We have structures in place that encourage and facilitate research in computational and translational neuroscience that reside at the interface of disciplines including engineering, applied mathematics and neuroscience. Our training covers the full-spectrum of state-of-the art methodologies that we consider essential for a successful career in the neurosciences. These include non-invasive functional MRI, applications of robotics and neuroprosthetics, advanced electrophysiological recordings, mouse transgenics, behavioral studies, molecular manipulations of neuronal genes and functional proteomics

描述（由申请人提供）：这个神经科学博士预科培训项目的中心目标是继续为博士预科学生提供个性化的高质量培训，帮助他们在研究生学习的中后期准备完成论文研究。我们提供广泛的、多学科的各级培训，在核心概念、技能、方法和对科学文献的高级理解方面打下坚实的基础。我们新修订的核心课程在基因、细胞、系统、认知、转化神经科学和神经系统疾病等层面指导学生。我们营造了一个不受传统学科界限限制的环境，鼓励研究生在这些学科的界面上工作。在教学的所有阶段，我们整合的技能被认为是必不可少的成功，独立的研究事业在神经科学。这些包括批判性思维和推理，有效的科学写作和口头陈述，科学审查过程的知识，以及道德培训。对于这个项目，我们将扩大最近的举措，以确保研究生有机会接触到神经科学的临床和疾病概念。这些措施包括将布朗大学临床医生的研讨会纳入我们的核心课程，参加布朗附属医院的神经病学、神经病理学和精神病学大查房；并强制要求新研究生参加第三年的疾病神经生物学课程。我们的大部分博士预科学员继续在学术界或生物技术行业从事神经系统的基础科学研究。我们希望在他们的早期培训中接触临床问题将对他们的研究生涯产生积极影响。布朗大学神经科学研究生项目的主要特点包括：卓越的研究以及卓越的教育和指导；跨学科和转化研究的历史，特别是在计算神经科学方面；还有一个小而高效的实验室环境，研究生在研究过程中是平等的伙伴。拟议中的培训项目有29名教师参与，他们来自布朗大学六个不同的院系，目标是约50名博士预科学员。教师培训师是一群杰出而充满活力的脑科学家，他们共同涵盖了从基因到认知的现代神经科学研究的范围。我们有适当的结构来鼓励和促进计算和转化神经科学的研究，这些研究位于学科的界面，包括工程，应用数学和神经科学。我们的培训涵盖了我们认为在神经科学领域取得成功必不可少的最先进的方法的全部范围。这些包括非侵入性功能MRI，机器人和神经假肢的应用，先进的电生理记录，小鼠转基因，行为研究，神经元基因的分子操作和功能蛋白质组学