IMPORTANCE OF PATERNAL CARE

父亲照顾的重要性

• 批准号: 8173072
• 负责人: Toni Elaine ZIEGLER
• 金额: $ 3.1万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8173072
• 关键词: American; Behavior; Biological Assay; Birds; Birth; Body Weight decreased; Breeding; Callithrix; Callithrix jacchus jacchus; Caring; Computer Retrieval of Information on Scientific Projects Database; Estradiol; Etiology; Family; Fathers; Fishes; Funding; Grant; Hormonal; Hormones; Human Biology; Infant; Infant Care; Institution; Journals; Methods; Monkeys; Neurosecretory Systems; Parenting behavior; Parents; Partner in relationship; Postpartum Period; Pregnancy; Primates; Prolactin; Publications; Reporting; Research; Research Personnel; Resources; Role; Sampling; Serum; Services; Source; Stimulus; Testing; Testosterone; United States National Institutes of Health; Variant; Weight; Weight Gain; design; experience; male; reproductive hormone; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To determine the facilitators of good parenting in primates. Prolactin has been implicated in promoting paternal care behaviors but little evidence of causality has been found to date except for birds and fish. This study was designed to examine the possible causal relationships between prolactin and male parenting behaviors, reproductive hormones, and physical changes in cooperatively breeding common marmosets, Callithrix jacchus. Fifteen parentally experienced fathers were studied over three consecutive infant care periods during two weeks prior and three weeks following their mates' parturition under three-treatment conditions: normal control pregnancy, decreased prolactin and elevated prolactin. The treatments significantly altered the serum prolactin levels in the fathers. Using three methods of determining a father's level of parental care: infant carrying, family effort and responsiveness to infant stimulus tests, we found that only the male's response to infant stimuli was altered by the hormone treatments. Lowering prolactin significantly reduced male responsiveness to infant stimuli but elevating prolactin showed the same effect. Hormonal sampling indicated that testosterone levels showed an inverse relationship to prolactin levels during a normal peripartum period and prolactin treatment reduced this relationship. Prepartum estradiol levels were significantly elevated during the lowered prolactin treatment and estradiol was significantly lowered postpartum with the elevated prolactin treatment. Father's weight decreased significantly by the third week of infant care during the normal treatment. Males in the elevated prolactin treatment lost little or no weight from prepartum while in the lowered prolactin treatment showed the most weight loss. The present findings did not distinguish a direct causal relationship of prolactin on behavior in experienced fathers but did find an interaction with other hormones and weight gain. This research used WNPRC Assay Services and the marmoset colony. Funding ended before this reporting period; publications have resulted. PUBLICATIONS: Ziegler TE, Prudom SL, Zahed SR, Parlow AF, Wegner F (2009). Prolactin's mediative role in male parenting in parentally experienced marmosets (Callithrix jacchus). HORMONES AND BEHAVIOR 56:436-443. PMCID: PMC2761515 Ziegler, TE, Prudom, SL, Zahed, SR. (2009). Variation in male parenting in the common marmoset monkey and its neuroendocrine control. AMERICAN JOURNAL OF HUMAN BIOLOGY, 21: 739-744. PMID: 19367571

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 目的：确定灵长类动物中良好育儿的促进者。 催乳素与促进父亲护理行为有关，但除了鸟类和鱼类外，几乎没有发现因果关系的证据。这项研究旨在检查催乳素与男性育儿行为，生殖激素以及合作繁殖的常见果果Callithrix Jacchus的物理变化之间可能的因果关系。在两周前的三个星期和三周后，在三个治疗条件下，在连续三个婴儿的护理期内对15个父母经历的父亲进行了研究：正常对照妊娠，催乳素降低和催乳素升高。这些处理显着改变了父亲的血清催乳素水平。使用确定父亲父母护理水平的三种方法：婴儿携带，家庭努力和对婴儿刺激测试的反应，我们发现只有男性对婴儿刺激的反应才通过激素治疗改变了。降低催乳素可显着降低男性对婴儿刺激的反应能力，但催乳素升高显示出相同的作用。激素采样表明，睾丸激素水平在正常周期表现出与催乳素水平的反比关系，而催乳素治疗降低了这种关系。在降低催乳素治疗期间，雌二醇的雌二醇水平显着升高，雌二醇通过催乳素治疗升高显着降低产后。在正常治疗期间，父亲的体重在婴儿护理的第三周显着降低。催乳素治疗升高的男性在降低的催乳素治疗中几乎没有或根本没有体重减轻，但体重减轻最大。目前的发现没有区分催乳素对经验丰富的父亲行为的直接因果关系，而是发现与其他激素和体重增加的相互作用。 这项研究使用了WNPRC测定服务和摩尔莫斯群落。 资金在此报告期之前结束；出版物已导致。 出版物： Ziegler TE，Prudom SL，Zahed SR，Parlow AF，Wegner F（2009）。催乳素在男性育儿中的介体作用在育儿经历的果mar（Callithrix jacchus）中。激素和行为56：436-443。 PMCID：PMC2761515 Ziegler，TE，Prudom，SL，Zahed，Sr。 （2009）。公共猴子猴子及其神经内分泌控制中男性育儿的变化。 《美国人类生物学杂志》，21：739-744。 PMID：19367571