WNPRC ASSAY SERVICES UNIT

这个子项目是众多研究子项目之一

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To provide core, campus and non-host investigators with sophisticated and specialized assay resources and expertise. Progress and Concerns From May 1, 2007 through January 31, 2008, Assay Services has received $175,978.25 as income from our charge backs for our service, $6,045 from charging base grant accounts and $7,434 for charging ourselves for validations and quality controls. We ran 46,630 determinations during this time. Assay Services' new initiatives during this time have been 1) iodinating for other labs for their RIA of protein hormones as a fee for service, 2) obtaining the expertise to initiate steroid and protein conjugation for our EIAs, 3) beoming the core lab for the Clinical Translational Science Award at the University of Wisconsin for translational studies, 4) continued use of multiple steroid analyses by LC/MS. Allocation of Resource Access Assay Services has an international and national client base. During the past year we ran samples for investigators from many different states and several countries. We primarily provide services for NIH based grants using nonhuman primate samples for hormonal determinations and more recently for translational studies. Assay Services has a website that is easily assessable to the scientific community: http://ink.primate.wisc.edu/~assay/assay.php Dissemination We have many clients who contact us via our website. Additionally, we attend meetings such as the American Society of Primatologists, Society of Behavioral Neuroendocrinology, and the Endocrine Society to make the nonhuman primate community aware of our services. We also receive clients from recommendations by previous clients. Training Assay Services continues to train graduate students, technical support, post doc and scientists to run their own samples as self-service. Sarah Carnegie, University of Calgary, visited the Assay Services Unit this last summer to to analyze reproductive hormones from fecals samples collected during an 18 month field study of Cebus capucinus. Valerie Schoff, Tulane University, also visited the lab during the summer to analyze Cebus capucinus samples. Sarie Van Belle, University of Wisconsin  Anthropology, trained and ran fecal samples for progesterone, estradiol and cortisol from Alouatta pigra. Liza Moscovice trained and analyzed urine and fecal samples for oxytocin, vasopressin, prolactin and testosterone in Papio ursinus. Elizabeth Becker trained and analyzed serum samples for corticosterone, testosterone and progesterone for Californica mus.