白藜芦醇、碳水化合物限制与前列腺癌进展-猫眼课题宝

白藜芦醇、碳水化合物限制与前列腺癌进展

批准号：

8310811

负责人：

Stephen Jay Freedland

金额：

$30.05万

依托单位：

DUKE UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

2008

资助国家：

美国

项目状态：

已结题

起止时间：

2008-09-15 至 2014-07-31

来源：

https://reporter.nih.gov/project-details/8310811

关键词：

Accounting Androgens Animals Apoptosis Body Weight Carbohydrates Caring Cessation of life Clinical Research Clinical Trials Complementary Medicine Data Development Diet Diet Modification Dietary Fats Dose Epidemiology Fat-Restricted Diet Fatty acid glycerol esters Foundations Future Goals Growth Health Human Hyperphagia In Vitro Insulin Insulin-Like Growth Factor Binding Protein 3 Insulin-Like Growth Factor I Intake Macronutrients Nutrition Malignant Neoplasms Malignant neoplasm of prostate Morbidity - disease rate Mus Necrosis Phenotype Phytochemical Proteins Public Health Reducing diet Relative (related person)Research Design Resveratrol Role Signal Transduction Solid Somatomedins Testing Transgenic Mice Transgenic Organisms United States Weight Weight Gain Work Xenograft procedure androgen independent prostate cancer base cancer cell cancer therapy cancer type feeding improved in vivo men mortality novel pre-clinical preclinical study prevent tumor tumor progression

项目摘要

项目成果

Stephen Jay Freedland的其他基金

相似基金

相关文献

中文摘要

翻译

公共卫生声明前列腺癌是美国男性发病和死亡的主要原因。在这我们的目标是开发新的无毒补充治疗方法，旨在减缓前列腺癌进展：饮食调整和植物药物。如果这些临床前研究成功，这将为未来在前列腺癌患者中进行的临床研究奠定坚实的基础，从根本上改变和改善对前列腺癌患者的护理的可能性。

英文摘要

PUBLIC HEALTH STATEMENT Prostate cancer is a major cause of morbidity and mortality among men in the United States. In this proposal, we aim to develop novel non-toxic complementary treatments aimed at slowing prostate cancer progression: dietary modification and phytopharmaceuticals. If these pre-clinical studies are successful, this will lay a solid foundation for future clinical studies among men with prostate cancer, which eventually stand the possibility of radically altering and improving care for men with prostate cancer.

期刊论文(16)

专著(0)

科研奖励(0)

会议论文

Racial differences in adipose tissue distribution and risk of aggressive prostate cancer among men undergoing radiotherapy.

DOI： 10.1158/1055-9965.epi-14-0236

发表时间： 2014-11

期刊：

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

影响因子： --

作者：

[Allott EH, Howard LE, Song HJ, Sourbeer KN, Koontz BF, Salama JK, Freedland SJ]

通讯作者： Freedland SJ

Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma.

DOI： 10.1097/cmr.0b013e3283426805

发表时间： 2011-02

期刊：

Melanoma research

影响因子： 2.2

作者：

[de Ridder GG, Gonzalez-Gronow M, Ray R, Pizzo SV]