Institutional Center Cores for Advanced Neuroimaging

高级神经影像机构中心核心

• 批准号: 8452942
• 负责人: KAMIL UGURBIL
• 金额: $ 54.5万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-30 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8452942
• 关键词: Institutional; Center; Cores; Advanced; Neuroimaging

DESCRIPTION (provided by applicant): The general aim of this proposal is to establish NINDS Institutional Center Core facilities that will augment the unique resources that exist at the Center for Magnetic Resonance Research (CMRR), University of Minnesota, for biomedical imaging, so as to maximize their utilization and impact on a large number of NINDS funded research projects on normal brain function and neurological disorders. This aim is based on the premise that developments in the last two decades have generated a plethora of magnetic resonance (MR) techniques, such as functional brain imaging (fMRI), neurochemical spectroscopy, perfusion imaging, diffusion imaging etc., that provide indispensable and otherwise unavailable measurement capabilities for studies of the brain in humans and in animal models of human diseased states. However, optimal use of these techniques requires advanced instrumentation, unique expertise, and complex auxiliary capabilities that include complementary measurements employing classical techniques (e.g. electrophysiology, and histology) and other imaging modalities such as PET. Access to these instrumentation and methodologies, especially at the cutting-edge, is virtually impossible in individual labs and requires interdisciplinary interactions in the area of spin-physics, RF engineering, signal and image processing, and brain sciences. The aim of this grant is to provide this access within the cooperative, multidisciplinary, and interactive research environment of CMRR, so as to enrich the effectiveness of and promote new research directions in a large number of ongoing NINDS funded research projects.

描述（由申请人提供）：该提案的总体目的是建立Ninds机构中心核心设施，以增加明尼苏达大学磁共振研究中心（CMRR）的独特资源，用于生物医学成像，以使其利用率最大化，并对NINDS资助的大量研究对正常的大脑功能和Neurology neurolodic andurords andurords andurords neurology andurords andurords andurords and neurology andurords and neurolology contimors进行影响。该目标基于以下前提：在过去的二十年中，发展产生了众多的磁共振（MR）技术，例如功能性脑成像（FMRI），神经化学光谱，灌注成像，扩散成像等，它们为人类脑部和人类脑部的不可或缺的测量状态提供了不可弥补的和否定性的测量状态。但是，这些技术的最佳使用需要高级仪器，独特的专业知识和复杂的辅助功能，包括采用经典技术（例如电生理学和组织学）以及其他成像方式（例如宠物）的补充测量。在单个实验室中，几乎不可能使用这些仪器和方法，尤其是在尖端，需要在旋转物理学，RF工程，信号和图像处理以及脑科学领域的跨学科相互作用。这笔赠款的目的是在CMRR的合作，多学科和互动研究环境中提供此访问，以丰富和促进许多正在进行的NINDS资助的研究项目中新的研究方向的有效性。