COGNITIVE PHENOTYPING: NEUROPSYCHIATRIC THERAPEUTICS (RMI)

认知表型:神经精神治疗 (RMI)

基本信息

  • 批准号:
    8363445
  • 负责人:
  • 金额:
    $ 1.01万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2011
  • 资助国家:
    美国
  • 起止时间:
    2011-08-01 至 2012-07-31
  • 项目状态:
    已结题

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The exploratory Center for Cognitive Phenomics (CCP) aims to accelerate identification and efficient measurement of cognitive phenotypes across syndromes and across species to advance interdisciplinary research on neuropsychiatric therapeutics. Cognitive abnormalities have been identified in all major neuropsychiatric disorders, offer quantitative phenotypes for genomic studies and clinical trials, and provide strong bridging relations to neural systems models. The CCP will iteratively refine cognitive phenotypes in interdisciplinary research using neurobehavioral, neuroimaging, and neuropsychopharmacological approaches to provide translational validation of physiological endophenotypes. The CCP will coordinate activities of a large group of experts at UCLA and elsewhere to: (1) generate cross-disorder and cross-species catalogs of phenotypes; (2) develop a phenotype selection algorithm to identify the most promising candidates for research; (3) design a phenomics database for empirical data representation, data mining, and hypothesis testing; and (4) support proof of- concept pilot projects. To advance these aims the CCP will initiate core services for: High Throughput Cognitive Phenotyping; Neuroimaging; and Translational Neuropsychopharmacology. The CCP will initially leverage UCLA campus-wide resources to provide bridging infrastructure and expertise in: Genomics, Pharmacogenomics and Statistical Genetics; Biostatistics and Psychometrics; Bioinformatics; Clinical Trial Design and Regulatory Affairs; and Bioethics. The CCP aims to overcome bottlenecks in the discovery of treatments for neuropsychiatric syndromes that are caused by the use of traditional behavioral "symptom" phenotypes, which are heterogeneous and overlapping, and difficult to translate to basic research. The long-term goal is establishment of a mature CCP that will provide the international research community with efficient, well validated phenotype assays; a cognitive phenomics data repository linked to genomics, proteomics, and other biological knowledge-bases; and novel strategies for interdisciplinary research on neuropsychiatric therapeutics.
这个子项目是利用这些资源的众多研究子项目之一

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

ROBERT M BILDER其他文献

ROBERT M BILDER的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('ROBERT M BILDER', 18)}}的其他基金

National Neuropsychological Network (NNN)
国家神经心理学网络 (NNN)
  • 批准号:
    10335125
  • 财政年份:
    2019
  • 资助金额:
    $ 1.01万
  • 项目类别:
National Neuropsychological Network (NNN)
国家神经心理学网络 (NNN)
  • 批准号:
    10550170
  • 财政年份:
    2019
  • 资助金额:
    $ 1.01万
  • 项目类别:
Genetic, Imaging, and Cognition study of Positive Valence Systems in Psychotic Syndromes
精神病综合征正价系统的遗传、影像和认知研究
  • 批准号:
    10468990
  • 财政年份:
    2018
  • 资助金额:
    $ 1.01万
  • 项目类别:
Genetic, Imaging, and Cognition study of Positive Valence Systems in Psychotic Syndromes
精神病综合征正价系统的遗传、影像和认知研究
  • 批准号:
    10248440
  • 财政年份:
    2018
  • 资助金额:
    $ 1.01万
  • 项目类别:
Genetic, Imaging, and Cognition study of Positive Valence Systems in Psychotic Syndromes
精神病综合征正价系统的遗传、影像和认知研究
  • 批准号:
    10019593
  • 财政年份:
    2018
  • 资助金额:
    $ 1.01万
  • 项目类别:
Multi-Level Assays of Working Memory and Psychopathology
工作记忆和精神病理学的多层次分析
  • 批准号:
    8839303
  • 财政年份:
    2014
  • 资助金额:
    $ 1.01万
  • 项目类别:
Multi-Level Assays of Working Memory and Psychopathology
工作记忆和精神病理学的多层次分析
  • 批准号:
    8691457
  • 财政年份:
    2014
  • 资助金额:
    $ 1.01万
  • 项目类别:
Multi-Level Assays of Working Memory and Psychopathology
工作记忆和精神病理学的多层次分析
  • 批准号:
    8881584
  • 财政年份:
    2014
  • 资助金额:
    $ 1.01万
  • 项目类别:
COGNITIVE PHENOTYPING: NEUROPSYCHIATRIC THERAPEUTICS (RMI)
认知表型:神经精神治疗 (RMI)
  • 批准号:
    8171066
  • 财政年份:
    2010
  • 资助金额:
    $ 1.01万
  • 项目类别:
COGNITIVE PHENOTYPING: NEUROPSYCHIATRIC THERAPEUTICS (RMI)
认知表型:神经精神治疗 (RMI)
  • 批准号:
    7955677
  • 财政年份:
    2009
  • 资助金额:
    $ 1.01万
  • 项目类别:

相似海外基金

HNDS-R: Connectivity, Inclusiveness, and the Permeability of Basic Science
HNDS-R:基础科学的连通性、包容性和渗透性
  • 批准号:
    2318404
  • 财政年份:
    2023
  • 资助金额:
    $ 1.01万
  • 项目类别:
    Standard Grant
Advancing the basic science of membrane permeability in macrocyclic peptides
推进大环肽膜渗透性的基础科学
  • 批准号:
    10552484
  • 财政年份:
    2023
  • 资助金额:
    $ 1.01万
  • 项目类别:
Computer Vision for Malaria Microscopy: Automated Detection and Classification of Plasmodium for Basic Science and Pre-Clinical Applications
用于疟疾显微镜的计算机视觉:用于基础科学和临床前应用的疟原虫自动检测和分类
  • 批准号:
    10576701
  • 财政年份:
    2023
  • 资助金额:
    $ 1.01万
  • 项目类别:
Bringing together communities and basic science researchers to build stronger relationships
将社区和基础科学研究人员聚集在一起,建立更牢固的关系
  • 批准号:
    480914
  • 财政年份:
    2023
  • 资助金额:
    $ 1.01万
  • 项目类别:
    Miscellaneous Programs
“L-form” bacteria: basic science, antibiotics, evolution and biotechnology
L 型细菌:基础科学、抗生素、进化和生物技术
  • 批准号:
    FL210100071
  • 财政年份:
    2022
  • 资助金额:
    $ 1.01万
  • 项目类别:
    Australian Laureate Fellowships
Developing science communication on large scale basic science represented by accelerator science
发展以加速器科学为代表的大规模基础科学科学传播
  • 批准号:
    22K02974
  • 财政年份:
    2022
  • 资助金额:
    $ 1.01万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Coordinating and Data Management Center for Translational and Basic Science Research in Early Lesions
早期病变转化和基础科学研究协调和数据管理中心
  • 批准号:
    10517004
  • 财政年份:
    2022
  • 资助金额:
    $ 1.01万
  • 项目类别:
Basic Science Core - Imaging
基础科学核心 - 成像
  • 批准号:
    10588228
  • 财政年份:
    2022
  • 资助金额:
    $ 1.01万
  • 项目类别:
UCSF - UCB TRAC Basic Science CORE
UCSF - UCB TRAC 基础科学核心
  • 批准号:
    10674711
  • 财政年份:
    2022
  • 资助金额:
    $ 1.01万
  • 项目类别:
Basic Science Core - Biosafety & Biocontainment Core (BBC)
基础科学核心 - 生物安全
  • 批准号:
    10431468
  • 财政年份:
    2022
  • 资助金额:
    $ 1.01万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了